Inthisstudy, researchersintroduced a lonelyexperimentalmouseto a newmousefriend, andobserved a significantincreaseinactivityofthe "lonelinessneurons".
Then, theygavethemouse a choicebetweenspendingtimealoneorwithanothermouse, andstudiedhowoptogeneticstimulationofthe "lonelinessneurons" influencedthemouse's choice.
Activationofthoseneuronscausedthemousetospendsignificantlymoretimewith a mousycompanion, indicatingthatwhenthoseneuronsfire, miceseekoutsocialinteraction.
Butwasthemouse's choicemotivatedbypositiverewardor a negativeexperience?
Todeterminethis, scientistsletmiceroamaroundin a boxthatcontainedtwoareas.
Whenthemousespenttimeinonearea, its "lonelinessneurons" werestimulated, andwhileintheotherarea, theywerenot.
Thisobservationledresearcherstosuggestthatactivityinthisbrainregionmightbeconnectedto a loneliness-likestatethatmotivatesmicetoseekoutsocialcontacttofeelbetter.
Thesefindingsreinforcetheevolutionaryviewthatlonelinessisactually a goodthing.