I got to go to buy this expensive software or to go to this course I heard about." It and I actually find all of these, what they have in common is more like the placebo effect, that you've spent so much money that perhaps you're going to put in more work because of that.

A major clinical trial of Semaglutide in adults showed an average weight reduction of around 15% when paired with an adjusted die and exercise routine compared to a placebo group, which demonstrated a little over 2% weight reduction.

Not sure how much of that is placebo,

The other group got placebo.

This is where the placebo effect comes into play.

In this double-blind, randomized, placebo-controlled trial, 13,970 patients 18 to 85 years of age with increased cardiovascular risk, who were unable or unwilling to take guideline-recommended doses of statins, were assigned to receive 180 mg of oral bempedoic acid, or placebo, daily.

Here's the mock stimulation group, sort of the placebo, as it were.

So goal setting and goal planning, um, seems to, for example, in our joint work, uh, in a random assignment, placebo-controlled longitudinal field study over the course of half of an academic year, uh, this, uh, brief intervention is able to improve GPA from school records as well from school records, uh, school attendance, uh, you know, being on time, and, uh, teachers who are blind to condition, their ratings of classroom conduct, uh, during that semester.

So thinking that all of these research tips will make me feel better can have a placebo effect of actually making me feel better.

But these broad positive claims from advocates or websites actually lead to the biggest problem with microdosing right now, which is that in double blind controlled studies, microdosing doesn't perform any better than a placebo.