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  • Imagine chowing down on a pastrami and pizza bagel sandwich, deep-fried and covered in more cheese.

  • Mouthwateringright? But then there's this nagging thought

  • Could this delicious monstrosity be speeding up my biological clock, ticking away my years?  

  • Well, thanks to a study that spills the beans on exactly how our diet influences our biological agewe're closer to that answer.

  • Let's digest this info together, along with some antacid, to find out if we can outsmart our body's biological clocks through the land of greens and genes.

  • Nonot those jeans — G-R-E-E-N-S. And you're already eating them. Okay, all right, well, here we go.

  • Hey there, welcome to Life Noggin.

  • Recentlyan innovative study was conducted by Stanford University that explored the impact of diet on health and age.

  • The study followed 22 sets of genetically identical twins over 8 weekswith one twin on a vegan diet and the other on an omnivorous diet.

  • What they found is that those on a vegan diet experienced improvements in heart health through lower levels of LDL cholesterol and an increase in beneficial gut bacteria.

  • Additionally, the vegan diet group showed a reduction in biological agesuggesting potential anti-aging effects of plant-based eating.

  • Okay, so you're eating a bunch of veggies and swearing off Mr. Mumu here, but how does one measure these changes in biological age or health?

  • Are you ready to get full-on some science?

  • Enter Methylation Risk Scores, or MRSs, a cutting-edge approach that dives deep into our DNA.

  • Unlike Polygenic RIS scores (PRS), which are fixed and based on the genes we inheritMRSs assesses the methylation patterns on our DNA.

  • These patterns are like biological bookmarksindicating which genes are turned on or offand can significantly influence our health and aging process.

  • Specifically, MRSs can be revolutionary in the medical field.

  • For exampleby reading DNA methylation patternswe can now diagnose diseases that were previously identifiable only by clinical observation, such as schizophrenia.

  • What's really cool is that MRSs enables us to predict the risk of developing diseases that lack traditional predictive measures, like Chronic Obstructive Pulmonary Disease (COPD),  

  • which currently isn't predicted but diagnosed when you're already sick.

  • This leap in predictive capability highlights not just the potential for early intervention but also the strength of our biological makeup.

  • Unlike PRS, these methylation patterns can change based on our lifestyle choices, environmentand notably, circling back, our diet.

  • Okay, so MRSs is a great thing. How can we influence our MRSs for the better?  

  • Let's take some notes, people.

  • Science points towards several strategies, like optimizing nutrient intake, engaging in regular physical activity, managing stress effectivelyand ensuring quality sleep.

  • Uh-oh, I'm in danger.

  • Each of these factors plays a pivotal role in how our genes express themselves.

  • They enhance our health, ageand well-being.

  • However, the real benefits of MRSs is that once these tools are createdwe can find the specific interventions which are most preventative.

  • Basically, there's a lot more helpfulness to be explored, and as the science of aging advances, there are newer, more precise methods that can determine our biological age,

  • such as advanced epigenetic testingwhich examines the modifications in our DNA

  • These methods stand out not just by measuring the accumulation of age-related molecular changes, but assessing the pace at which these changes occur.

  • And that brings us to the sponsor of today's video.

  • So, be honest, do you think your diet is helping or hurting your biological age?

  • Based on your diet, how old do you feel?

  • Thank you to our sponsor, True Diagnostic.

  • True Diagnostic is an epigenetic research and testing company specializing in biological aging based on DNA methylation.

  • With the ability to test more than 1 million locations on your DNA, True Diagnostic takes biological aging insights to the next level.  

  • They only use published algorithms with documented and proven links to health outcomes.  

  • To learn more about other aging and health-related secrets you can unlock from your epigeneticsvisit truediagnostic.com or click the first link in the description.

  • Click here to figure out if we can turn back our biological clocks, or click here to watch this video.

  • As always, my name is Blocko, this has been Life Noggin. Don't forget to keep on thinking.

Imagine chowing down on a pastrami and pizza bagel sandwich, deep-fried and covered in more cheese.

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B1 US biological methylation diet dna aging age

Your Relationship With Food Is Complicated.

  • 14 1
    林宜悉 posted on 2024/04/19
Video vocabulary

Keywords

potential

US /pəˈtɛnʃəl/

UK /pəˈtenʃl/

  • noun
  • someone's or something's ability to develop, achieve, or succeed
  • The possibility of something happening or some quality that somebody/something has.
  • A person who is being considered for a job, position, award, etc.
  • A latent quality or ability that may be developed.
  • adjective
  • Capable of happening or becoming reality
  • Having or showing the capacity to develop into something in the future.
  • Possible of becoming something
  • Possible, able to happen; something that can develop or become a reality.
  • Possible; likely to develop into a particular type of person or thing in the future
  • Possible or likely in the future
  • other
  • The ability to develop into something in the future
  • The capacity to develop into something in the future
  • The amount of energy that something has stored
  • The possibility of something happening or some quality that somebody/something has
  • other
  • The capacity to develop into something in the future
  • The amount of energy that something has stored in it because of its position or condition
  • The possibility of something happening or some quality that somebody/something has
approach

US /əˈprəʊtʃ/

UK /ə'prəʊtʃ/

  • other
  • The means or opportunity to reach something.
  • other
  • To come near or nearer to someone or something in distance or time.
  • other
  • To come near or nearer to someone or something in distance or time.
  • To speak to someone about something, often making a request or proposal.
  • noun
  • Means of reaching a place, often a road or path
  • An initial proposal or request made to someone.
  • A way of dealing with something.
  • Request of someone with a specific goal in mind
  • Specific way to handle a project, task, problem
  • verb
  • To get close to reaching something or somewhere
  • To request someone to do something specific
process

US /ˈprɑsˌɛs, ˈproˌsɛs/

UK /prə'ses/

  • verb
  • To organize and use data in a computer
  • To deal with official forms in the way required
  • To prepare by treating something in a certain way
  • To adopt a set of actions that produce a result
  • To convert by putting something through a machine
  • noun
  • A series of actions or steps taken in order to achieve a particular end.
  • A summons or writ to appear in court or before a judicial officer.
  • A systematic series of actions directed to some end
  • Dealing with official forms in the way required
  • Set of changes that occur slowly and naturally
  • A series of actions or steps taken in order to achieve a particular end.
  • other
  • To perform a series of operations on (data) by a computer.
  • To deal with (something) according to a particular procedure.
  • Deal with (something) according to a set procedure.
  • To perform a series of mechanical or chemical operations on (something) in order to change or preserve it.
  • To perform a series of mechanical or chemical operations on (something) in order to change or preserve it.
  • Take (something) into the mind and understand it fully.
  • other
  • Deal with (something, especially unpleasant or difficult) psychologically in order to come to terms with it.
description

US /dɪˈskrɪpʃən/

UK /dɪˈskrɪpʃn/

  • noun
  • Explanation of what something is like, looks like
  • A spoken or written account of a person, object, or event.
  • A summary of a computer program or file.
  • The act or method of describing
  • A summary of the qualities and features of a product or service
  • The type or nature of someone or something.
impact

US /ˈɪmˌpækt/

UK /'ɪmpækt/

  • noun
  • A striking effect or result to hit with force
  • Act or force of one thing hitting something else
  • A marked effect or influence.
  • other
  • To collide forcefully with something.
  • verb
  • To hit or strike someone or something with force
  • other
  • (especially of a tooth) wedged so that it cannot erupt.
  • To have a strong effect on someone or something.
develop

US /dɪˈvɛləp/

UK /dɪ'veləp/

  • verb
  • To explain something in steps and in detail
  • To create or think of something
  • To grow bigger, more complex, or more advanced
  • To make a photograph from film
  • other
  • To invent something or cause something to exist
  • To start to suffer from an illness or other medical condition
  • To improve the quality, strength, or usefulness of something
  • other
  • To (cause something to) grow or change into a more advanced, larger, or stronger form
cholesterol

US /kəˈlestərɔ:l/

UK /kəˈlestərɒl/

  • noun
  • Substance in the body that may cause heart disease
  • A test to measure the amount of cholesterol in your blood.
  • other
  • A type of fat produced by the liver and also found in some foods, which can cause heart disease if there is too much of it in the blood.
bacteria

US /bækˈtɪriə/

UK /bæk'tɪərɪə/

  • noun (plural)
  • Plural form of bacterium; a large group of single-celled microorganisms.
  • noun
  • The very small creatures that can cause disease
gut

US /ɡʌt/

UK /ɡʌt/

  • verb
  • To destroy the inside of a building , e.g. by fire
  • To remove the internal parts of an animal or fish
  • noun
  • Stomach and internal organs of digestion
  • Guts courage; emotional strength
measure

US /ˈmɛʒɚ/

UK /ˈmeʒə(r)/

  • noun
  • Plan to achieve a desired result
  • A plan or course of action taken to achieve a particular purpose.
  • A certain amount or degree of something.
  • A division of time in music, usually consisting of a fixed number of beats.
  • Tool used to calculate the size of something
  • A standard unit or system used for measuring.
  • other
  • To assess or estimate the extent, quantity, or effect of something.
  • To determine the size, amount, or degree of an object or substance by comparison with a standard unit.
  • verb
  • To determine the value or importance of something
  • To calculate size, weight or temperature of
  • other
  • To take actions to achieve a particular purpose.