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    telomere

    US /'teləˌmɪr/

    ・

    UK /'teləmɪə/

    A1
    n.NounEither (free) end of a eukaryotic chromosome
    Telomeres act as caps to keep the sticky ends of chromosomes from randomly clumping together

    Video subtitles

    Why women should FAST differently than men… | Exercise & Nutrition Scientist Dr Stacy Sims

    07:57Why women should FAST differently than men… | Exercise & Nutrition Scientist Dr Stacy Sims
    • And unfortunately, a lot of those times we look at clinical research and it gets transposed over to health and fitness without actually asking if it's viable. So then we look at the lower end of the fitness population. People are just learning to move and wanting to move. And like, I also want to lose more body fat so that I can move better. Oh, I'll start fasting. And when we see a lot of the like push on it, it comes from male data again. So when we start looking at women and a lot of women used to come with their partners to see me and say, I don't understand. We're both doing the same kind of fasted training. He's leaning up and getting fitter. I'm putting weight on and getting slower. I'm like, okay, well we have to separate it out, right? If you're a woman, you want to fast for all the health reasons that we hear about with regards to telomere length, improving longevity, improving our body's metabolic control. Then we work with our circadian rhythm where we stop eating at dinner. So we have dinner and we don't eat two to three hours before bed.

      And unfortunately, a lot of those times we look at clinical research and it gets transposed over to health and fitness without actually asking if it's viable. So then we look at the lower end of the fitness population. People are just learning to move and wanting to move. And like, I also want to lose more body fat so that I can move better. Oh, I'll start fasting. And when we see a lot of the like push on it, it comes from male data again. So when we start looking at women and a lot of women used to come with their partners to see me and say, I don't understand. We're both doing the same kind of fasted training. He's leaning up and getting fitter. I'm putting weight on and getting slower. I'm like, okay, well we have to separate it out, right? If you're a woman, you want to fast for all the health reasons that we hear about with regards to telomere length, improving longevity, improving our body's metabolic control. Then we work with our circadian rhythm where we stop eating at dinner. So we have dinner and we don't eat two to three hours before bed.

    • If you're a woman and you want to fast for all the health reasons that we hear about with regards to telomere length, improving longevity, improving our body's metabolic control, then we work with our circadian rhythm, where we stop eating at dinner.

      If you're a woman and you want to fast for all the health reasons that we hear about with regards to telomere length, improving longevity, improving our body's metabolic control, then we work with our circadian rhythm, where we stop eating at dinner.

    B1

    遺伝子の研究者だけど質問ある? | Tech Support | WIRED Japan

    14:20遺伝子の研究者だけど質問ある? | Tech Support | WIRED Japan
    • They called it telomere to telomere.

      They called it telomere to telomere.

    • They called it telomere to telomere.

      They called it telomere to telomere.

    B2

    You're Actually More Than One Age

    04:24You're Actually More Than One Age
    • One of them is telomere length.

      One of them is telomere length.

    • Understanding your rate of biological aging, epigenetic biological age, and telomere length

      Understanding your rate of biological aging, epigenetic biological age, and telomere length

    B1

    The Science of Aging

    02:06The Science of Aging
    • This also helps to explain why life expectancy is a strongly heritable trait from your parents, because you got your initial telomere length from them.

      This also helps to explain why life expectancy is a strongly heritable trait from your parents, because you got your initial telomere length from them.

    • telomere length from them.

      telomere length from them.

    B2

    Cancer May Have Finally Met Its Match!

    04:09Cancer May Have Finally Met Its Match!
    • But there are ways to lengthen the telomere.

      But there are ways to lengthen the telomere.

    • But there are ways to lengthen the telomere.

      But there are ways to lengthen the telomere.

    B1

    Mindfulness Stress Reduction And Healing

    14:43Mindfulness Stress Reduction And Healing
    • But a couple of years ago at UCSF, in, uh, the laboratory of Liz Blackburn, Alyssa Epple, who a-actually happens to be a mindfulness teacher, but, uh, is a young, uh, assistant professor at UCSF, did a study looking at the rate at which the repeat chromosome the repeat subunits at the ends of all of our chromosomes, which are called telomeres and which are required for every cell division in every cell in our body that divides, uh, that it turns out that stress, chr long-term chronic stress, can accelerate the rate of telomere degradation enormously.

      But a couple of years ago at UCSF, in, uh, the laboratory of Liz Blackburn, Alyssa Epple, who a-actually happens to be a mindfulness teacher, but, uh, is a young, uh, assistant professor at UCSF, did a study looking at the rate at which the repeat chromosome the repeat subunits at the ends of all of our chromosomes, which are called telomeres and which are required for every cell division in every cell in our body that divides, uh, that it turns out that stress, chr long-term chronic stress, can accelerate the rate of telomere degradation enormously.

    • So if you if stress increases the rate of telomere degradation, I mean, you can't get more somatic and molecular than that in terms of evidence that stress does ha has potentially, if it's not mitigated, the, the, the consequence of basically, uh, increasing aging.

      So if you if stress increases the rate of telomere degradation, I mean, you can't get more somatic and molecular than that in terms of evidence that stress does ha has potentially, if it's not mitigated, the, the, the consequence of basically, uh, increasing aging.

    B1

    Change your Mind Change your Brain: The Inner Conditions...

    59:29Change your Mind Change your Brain: The Inner Conditions...
    • And then maybe next year, something that might make the big time sort of news, we are now studying the aging process, which has to do, some of you might know, at the end of the DNA, the chromosome, there are freed, what you call telomere.

      And then maybe next year, something that might make the big time sort of news, we are now studying the aging process, which has to do, some of you might know, at the end of the DNA, the chromosome, there are freed, what you call telomere.

    • That's more like in a meditation sort of workshop for three months, a significant decrease of the diminution of the telomere.

      That's more like in a meditation sort of workshop for three months, a significant decrease of the diminution of the telomere.

    B1

    How Long Will You Live?

    06:26How Long Will You Live?
    • So every time a cell divides, it loses some of the telomere. They estimate about 200 base pairs.

      So every time a cell divides, it loses some of the telomere. They estimate about 200 base pairs.

    • So the telomere, and the telomere getting shorter is like your molecular clock. The cellular clock inside each cell that tells it how many times it has divided.

      So the telomere, and the telomere getting shorter is like your molecular clock. The cellular clock inside each cell that tells it how many times it has divided.

    B1

    Do We Have to Get Old and Die?

    02:58Do We Have to Get Old and Die?
    • since these lost bits come from the telomere end caps that don't encode important information.

      since these lost bits come from the telomere end caps that don't encode important information.

    • Age-defying species like naked mole rats, however, pump out high levels of a telomere-rebuilding enzyme that enables them to keep on replacing old and dysfunctional cells indefinitely.

      Age-defying species like naked mole rats, however, pump out high levels of a telomere-rebuilding enzyme that enables them to keep on replacing old and dysfunctional cells indefinitely.

    B2

    The Scientific Power of Meditation

    03:03The Scientific Power of Meditation
    • And a shortened telomere length has been linked to several diseases such as cardiovascular disease, diabetes, Alzheimer's, and cancer.

      And a shortened telomere length has been linked to several diseases such as cardiovascular disease, diabetes, Alzheimer's, and cancer.

    • Amazingly, when cancer survivors completed a meditation program, their bodies showed significant increases in telomere length.

      Amazingly, when cancer survivors completed a meditation program, their bodies showed significant increases in telomere length.

    B2