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  • Topic: Caffeine.

  • How does coffee keep you awake?

  • By throwing an overnight party.

  • No.

  • When we perform our daily activities like thinking and playing, a by product called adenosine is produced.

  • Adenosine slows down the brain activity.

  • But how?

  • In our brain, there are adenosine receptors which are perfectly molded for this adenosine.

  • When the adenosine binds to these receptors.

  • It activates them, causing to slow down the brain activity and thus making us feel sleepy.

  • However, drinking coffee keeps us awake and we don't feel sleepy.

  • This is because coffee contains a drug called caffeine which after digestion reaches our brain.

  • Caffeine is structurally similar to adenosine.

  • Being similar, caffeine binds to the adenosine receptors and thus blocks the adenosine from binding.

  • Hence, as adenosine does not bind, our receptors don't slow the brain activity.

  • As a result, we remain awake.

Topic: Caffeine.

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