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  • Ever wonder why both coffee and alcohol have the unfortunate tendency to make you pee?

  • Well aside from the fact that you may have been binge drinking both of these substances

  • Hopefully not at the same time. There are actually some simple biological processes at work when nature decides to call.

  • Your pituitary gland which resides the base of the brain controls the release of a hormone known as antidiuretic hormone.

  • Or ADH for short. ADH is secreted by the pituitary gland enters the bloodstream and is then carried to the kidney the kidney

  • among other things is responsible for monitoring

  • How much water is in your body and whether or not you can afford to get rid of it

  • In times of dehydration ADH is responsible for retaining water in your body by inducing the production of aquaporins in the kidney

  • Aquaporins are proteins embedded in the kidneys cell membrane that regulate the flow of water in this case allowing water to be reabsorbed back into

  • The body so the less water you've got more adh which means greater production of aquaporins and more water reabsorbed

  • So instead of letting it out

  • You keep it in. Think of it

  • Like a glass of water when you're really thirsty

  • The aquaporins act like a straw and allow for the water to flow back into your body. More straws equals more water reabsorbed

  • So what does ADH have to do with caffeine or alcohol?

  • Well, both caffeine and alcohol inhibit the release of ADH by the pituitary gland and as a result the

  • Aquaporins are not created to reabsorb water and the amount of water in your pee increases

  • This explains why once you've had your morning coffee or at least a couple beers on the patio a pee break is usually soon followed

  • In the case of alcohol this inhibition of adh unfortunately contributes to something known as a damn hangover this also explains

  • Why urine can seem clear during consumption and look like Tropicana orange juice the next morning. Are you sure you want coffee Frank?

  • That's better

  • (music)

  • (music)

Ever wonder why both coffee and alcohol have the unfortunate tendency to make you pee?

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