Name: (CC) Top 200 Drugs Chapter 5 Neuro / Mental Health Pharmacology by Suffix (Memorizing Pharmacology)
Uploaded: 2018-06-18T15:30:49.000Z
Duration: 19 min 28 s
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Okay let's go over chapter five neuro of
our review so let's start with local

Adverbs of degree

anesthetics and these are OTC and what a
local anesthetic is it's just something

that's going to numb a certain area.
Anesthetics, when injected, will make a

person pass out but what I want to talk
about is the ester vs the amide so

benzocaine is an ester it's a type of
organic chemistry molecule and that

tells you that the esters we don't
really want to inject because they can

become allergenic where a
patient might have an allergic reaction

lidocaine has less of that allergenicity
but they're both related by this -caine

stem c-a-i-n-e and that might look like
cocaine and that's right because cocaine

was one of the original anesthetics and
they found or developed some anesthetics

that weren't addicting but if you look
at Anbesol you see two of the letters

from the word numb so that's one way to
remember that one and then Solarcaine

Solarcaine takes the -caine ending that's
still frowned upon by the World Health

Organization but solar meaning sun so
we're using something to take care of

the pain from a sunburn but lidocaine
has many uses, an injectable in an

emergency, patch, some other different
things that it can be used for. OTC anti-

vertigo so meclizine if you put this, if
I were to do meclizine in small letters

like this, m-e-c-l-i-z-i-n-e
you could kind of put this C in this L

together to make a D and then you see
dizzy so it's for dizziness but the

brand name's Dramamine that you might
know but there was also a brand name

that was a prescription item, Antivert
for anti vertigo but that one told the

whole story, anti-vertigo. Another OTC
under neuro would be a sedative

hypnotic and we see diphenhydramine you
might say well I remember that one but

that was an antihistamine you told me
and that's what's kind of infuriating

about pharmacology is that things can be,
for prescription drugs can be for many

different things and all this is OTC but
diphenhydramine as an adverse effect

made someone drowsy but here we're using
that side-effect as a good thing so

tylenol acetaminophen
diphenhydramine the antihistamine that

makes you tired Tylenol PM and that PM
means post-meridian after literally

afternoon but we just use it at night
time so Tylenol PM is something used at

night time sometimes sleep is disturbed
because of pain and that's what the

acetaminophen is there for.
Benzodiazepine-like sedative hypnotics

now we're going to the prescription
items and benzodiazepine-like means

it's not a benzodiazepine but it works a
little like one so eszopiclone with the

-clone stem and we see this es- again so
the S isomer and you can think of Luna

or rest in Lunesta
and then zolpidem -pidem is the stem, p-i-d-e-m

and this is Ambien or Ambien CR, Ambien
controlled release so Ambien works to

help somebody fall asleep but if the
person has trouble staying asleep the

controlled release, much longer acting
version works well. Melatonin receptor

agonist so ramelteon the -melteon is
the stem and it looks like melatonin for

a reason because it is a melatonin
receptor agonist and you can think of

Rozerem, roz- rhymes with doze, REM for
rapid eye movement sleep, so a lot of

hints in these brand names certainly
worth remembering. So those are some

OTC neuro drugs something to help you
sleep. In the next column we're going to

go into antidepressants and how those
can help us. The first thing that throws

students off is the classifications as
SSRI, SNRI, TCA, MAOI and each one has

its own acronym
so an SSRI is a selective serotonin

reuptake (I didn't think about space
there) inhibitor okay and that means that

serotonin is going to normally be 
re-uptaken or if you want to think of it as

recycling that's maybe a better way but
instead what happens is we inhibit that

recycling it stays in the synapse and
it's supposed to make the patient

happier. It's that hypothesis of norepinephrine

and serotonin not having enough of
it so there's five of them I'm going to

go over citalopram and escitalopram we
see two drugs with the same root just

like we saw esomeprazole and omeprazole.
Celexa was the first one that came out

it reminds me of relaxed
these SSRIs can also be used for anxiety

and then Lexapro you can think of a
professional upgrade from the first one

so it takes part the ending of Celexa
and then just adds -pro to make Lexapro

but those are related in the escitalopram is supposed to be better than the

citalopram. The -traline stem for Zoloft
so it lofts your mood and then the

-oxetine. So -oxetine is a little bit tricky
the adopted names council calls -oxetine

a fluoxetine-like entity but fluoxetine
and paroxetine are SSRIs then we're

going to see that duloxetine is an SNRI
and later we're going to find a non

stimulant ADHD medication atomoxetine so
this -oxetine ending you really have to

be careful. Fluoxetine is
interesting it's got two brand names

Prozac was the first brand name that
came out it was

antidepressant sounds like a strong drug
with the P, Z and the C or with a K sound

and then Sarafem I'm not sure what they
were going for a seraphim it's like the

highest angel so maybe it was the work
of angels but that's for something

called premenstrual dysphoric disorder,
PMDD. Paroxetine, Paxil and then

Paxil controlled release so again
another medication that works a little

bit longer. Then we have the serotonin
norepinephrine reuptake inhibitor and

I'll try to do a little better job with
my writing here serotonin norepinephrine,

inhibitor and so we're just affecting
different neurotransmitters where

selective serotonin reuptake inhibitor
was just serotonin now we're talking

about serotonin and norepinephrine
again the -oxetine be careful with that

it's supposed to indicate a SSRI
Cymbalta so my mnemonic was to remember

that symbol players all would always
seem to be happy and alta means above in

Spanish so higher mood maybe. Then the
-faxine is the stem here in

venlafaxine and for Effexor so that's a
way to remember that one. So the TCA so

this SNRI and SSRI are are both named
after neurotransmitters but

amitriptyline is named after or the tricyclic antidepressant is named after the

three rings so you can see that -t-r-i- in
the stem -tripyline and Elavil elevates

your mood. Isocarboxazid I didn't
have a stem that I saw but I had a

student that said I sew car boxes and
it just seemed very sad so it's a monoamine

oxidase inhibitor so mono, m-o-n-o, a-m-i-n-e and oxidase inhibitor and

what that monoamine really means is
that we're still kind of going back to

serotonin which is a monoamine and that
we're affecting it we're just calling it

by a different name.
Smoking cessation so bupropion was first

an antidepressant it was Wellbutrin
so ideally you would get well or get out

of the rut you're in so you see the r-u-t
and then -i-n in there but then they

found that a lot of these
antidepressants stop smoking so though

this is great let's make it an anti
smoking drug so they renamed it Zyban or

repackaged it that way.
Varenicline it's chantix so the new

-nicline stem indicates a smoking cessation
medication and and I had a student that

said in a southern accent oh when I take
varenicline on their inclined to quit so

or with Chantix, my chant is that I
don't need my fix so anyway it just

stuck in my head. So these are
antidepressants all the way down to

bupropion which can also be used for
smoking cessation then varenicline is

Subtitles ListPlay Video

(CC) Top 200 Drugs Chapter 5 Neuro / Mental Health Pharmacology by Suffix (Memorizing Pharmacology)

anxiety

perception

term

dopamine