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  • This episode of Dnews was proudly made possible by the all-new 2015 Subaru Legacy. It’s

  • not just a sedan, it’s a Subaru.

  • You know those people who claim that they actually ENJOY exercise? Well it turns out,

  • they may be right. Damn it.

  • Hey guys, Tara here for Dnews - and try as we might, some of us just seem predisposed

  • to loving exercise. You get addicted to the endorphins, they say - and even though I personally

  • can’t understand what that’s like, it turns out there IS a part of our brains dedicated

  • to that - and it may explain why some people are more motivated to exercise than others.

  • Scientists at the Seattle Children’s Research Institute have discovered a tiny region of

  • the brain in mice - called the dorsal medial habenula - that controls their desire to exercise.

  • It’s also responsible for mood regulation and motivation, but its similarity to a structure

  • in human brains - means it could lead to improved treatments for depression, which typically

  • coincides with a lack of motivation.

  • The link between exercise and depression - has been proven time and time again. “Changes

  • in physical activity and the inability to enjoy rewarding or pleasurable experiences,

  • are two of the hallmarks of major depression” - so it makes sense that exercise would be

  • one of the more effective treatments for it. But the brain pathways responsible for exercise

  • motivation haven’t been well understood - until now.

  • For their study, a team of researchers examined 3 different groups of mice. The first group,

  • was a control. The second group, was genetically engineered to have their dorsal medial habenula

  • blocked - and the third group, were given the option of hyperactivating their dorsal

  • medial habenula, using laser technology.

  • Sure enough, the second group, whose brain region was blocked - were much more lethargic

  • than the control mice. Meaning even though they were physically capable of running on

  • their wheel - they just didn’t want to.

  • On the flip side, the third group of mice - had the option of either activating or suppressing

  • their dorsal medial habenula, by turning one of two response wheels. Turns out, mice strongly

  • preferred activating that area, as opposed to suppressing it. And that signifies that

  • this part of the brain is strongly tied to rewarding behavior.

  • It makes sense that the mice would choose that option, too. After all, nobody WANTS

  • to be depressed or lazy - it’s just something that happens. So you can imagine how useful

  • a drug would be, that specifically targets and activates that area.

  • Depression may be a well-understood disease, but the treatments for it - are still lacking.

  • So researchers hope that this discovery - can help develop better therapies for people who

  • lack the motivation to help themselves.

  • What do you guys think? Aside from the depression aspects, would you take a drug that made you

  • more motivated to exercise? Of course you would. Let us know your thoughts in the comments below - and as always,

  • thank you guys for watching!

This episode of Dnews was proudly made possible by the all-new 2015 Subaru Legacy. It’s

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