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  • Hi, my name is Sue Pascoe and I am a staff writer at the Palisadian Post, which

  • is a weekly newspaper newspaper in the Pacific Palisades [Los Angeles, CA], and I do the monthly

  • "Healthy Column"

  • and uh... I'm nothing healthy right now, but [Sue Laughs]

  • anytime one of our readers has an issue about fertility, about

  • miscarriages, about anything to do with reproductive, I go to speak to one of the

  • top fertility specialists in the United States, Dr. Ingrid Rodi, to help me

  • clarify, so that I am able to explain to our readers what's going on.

  • and today

  • I'm wondering -

  • 'What do you do if you're infertile? What - How do you know if you're infertile?'

  • and

  • I thought maybe Dr. Rodi could help us.

  • well um -

  • the first thing that

  • that couples need to know is that when they're considering

  • getting pregnant

  • they should consult their

  • family doctor or gynecologist

  • for preconception counseling. That means going in before they actually get

  • pregnant

  • to determine if there are any changes in the medications that they need, or if they have

  • any medical problems that might

  • complicate their pregnancy

  • and if there are any genetic

  • mutations that they're at risk for

  • and

  • the gynecologist will go over all those things and

  • give them the go-ahead -

  • Start her on

  • vitamins and on

  • folic acid -

  • SP: Oh so you should be taking vitamins even before you conceive?

  • IR: Yes, at least about

  • three months before.

  • There's also- SP: But it used to be so easy! Couldn't you just go and get pregnant

  • and that was it? Why do I have to go see my doctor before i even try?

  • IR: Well, you know, you want to optimize,

  • you know the

  • the chance that

  • the pregnancy is going to be

  • as easy as possible and that the baby's going to be as healthy as possible.

  • and once -

  • you know - the couples have been given the go-ahead

  • IF the woman is under thirty,

  • they're usually -

  • it's usually suggested that they try for a year.

  • SP: Okay, now by 'trying for a year' -

  • What does that mean?

  • IR: That means either - SP: I mean how many times am I having sex a week? What are we

  • talking here? IR: Right. That means either

  • just having sex regularly, meaning

  • three to four times a week

  • or using an ovulation prediction kit

  • which tells her

  • when she's going to ovulate.

  • So- SP: Okay, so

  • we've all seen it on TV - 'Honey! Honey! I'm ovulating! Come home quick!' Is that

  • really accurate?

  • IR: Well it's very helpful.

  • Especially if couples

  • are frequently out of town

  • and they're really trying to maximize

  • the timing,

  • then the kit is very helpful.

  • SP: Okay, so then

  • I'm under thirty and I'm having sex regularly or I'm using an ovulation kit - now

  • there is an old wives tale too, that after you have sex, if you're a woman you should put

  • your feet up -

  • does that actually have any truth to-

  • IR: No SP: Oh, okay so - IR: As long as everything is where it is supposed to be

  • you don't have to do anything. SP: You don't have to lay down for another hour, okay.

  • [Sue snaps her finger] Drat. Okay so now I'm under thirty and having sex regularly for a year

  • and i haven't gotten pregnant.

  • IR: Okay, so then, the couple comes back.

  • Or - if the woman is trying to get pregnant on her own - she comes back

  • and we look for for those areas which are considered deal breakers so

  • you need to be ovulating

  • SP: Why wouldn't I be ovulating? Doesn't every woman ovulate?

  • IR: Not every woman ovulates, and not every woman ovulates regularly.

  • SP: Oh, really? IR: So- SP: So if I'm one of those people that doesn't have a period

  • every month, would I be one of those 'irregular ovulators?' IR: Yes.

  • SP: Is that normal?

  • No, it's normal to have a period every month.

  • And if a woman is having a period

  • where the interval is more than five weeks

  • then she may ovulate but she doesn't ovulate regularly.

  • or at least not

  • or at least not every four weeks.

  • can you as a doctor

  • change that then? So that she can ovulate more regularly?

  • IR: Yes, there are medications we can give her to ovulate more regularly,

  • - in most cases.

  • okay so one of the things is then, if I come in, having that problem, you

  • check for regular ovulation.

  • IR: Right, the next thing we need to know is

  • if the man has sperm

  • and whether he has an adequate number of sperm.

  • And we do a semen analysis for that.

  • SP: Okay,

  • so,

  • what would be adequate number?

  • IR: Well- SP: I thought it only took one?

  • IR: Yeah, it only takes one, BUT uh... they have a long way to swim all the way from the cervix all the way up

  • to where fertilization occurs.

  • so you need actually more than one.

  • IR: You need about- SP: Or you need a SUPER super sperm to get the job done. spurted

  • IR: Right so you need - the normal semen analysis would have

  • twenty million

  • per CC.

  • and the usual volume is about-

  • at least two CCs per ejaculate.

  • SP: Okay, now so when you say 'CC' - how are we talking - a teaspoon full? Or

  • are we talking a pin head? What are we talking?

  • IR: Several drops certainly

  • SP: Several drops, okay.

  • IR: So that's measured in the lab

  • so they measure that.

  • SP: Okay so my partner who might not be thrilled about this will go to a lab

  • and produce a little

  • petrie dish full of semen to be looked at. IR: Exactly.

  • and then we also need them to be swimming

  • in the forward direction.

  • SP: No backstrokers?! IR: No backstrokers, well as long as they go forward [both laugh]

  • so we look at

  • both the count,

  • the motility, and how many of them look normal.

  • So one of the things that we're looking at is

  • whether the,

  • whether the sperm

  • have normal heads

  • SP: [pointing at diagram] One's a two header.

  • Some of the sperm have two heads?

  • IR: some of them have two heads and -

  • SP: Will that give you twins, if you have two heads?

  • IR: they typically don't do much of anything.

  • and some of these have two tails.

  • so you really want- SP: This one looks like a pointy head

  • he's not a good swimmer then either.

  • IR: No, all of these -

  • this is the normal one [points] and all of these are not so good.

  • SP: So could one of them make it up there or probably not? IR: Probably not.

  • This is the

  • best way to get up there.

  • okay, so if you go in then and you find out that

  • the problem is the sperm

  • then what do you do? IR: Then there are specialists

  • who evaluate the male and see

  • if there's anything they can do to improve the situation

  • if not then we sometimes have to

  • treat the

  • woman to compensate for the problems in the man. One of those treatments is

  • insemination

  • 'Artificial insemination' or 'in Vitro Fertilization.'

  • SP: Okay so now

  • so I'm sorry to sort of goad this, but I haven't heard much about

  • what - how can a man

  • improve? I mean what -

  • just not be as stressed as much? Would that

  • make better sperm? IR: Well, one of the

  • things the male

  • fertility specialist will look at is whether he's on any medications that

  • have a bad effect on the sperm.

  • Men who

  • smoke marijuana

  • often have sperm that are pretty slow swimmers so- [Sue Laughs]

  • SP: And they get munchies on the way up, I'm sure.

  • IR: Yeah - it's not enough for contraception

  • so I don't mean to suggest that marijuana is contraception, but it may slow them down.

  • so they have an

  • evaluation of their hormones

  • and a physical exam

  • and if all of that turns out to be normal, we can

  • inject the sperm into the egg

  • during in vitro fertilization.

  • SP: Okay, so now we've gone through:

  • a possible ovulation problem, a possible sperm problem,

  • what else might you evaluate me for? You find out that I am ovulating fine, the sperm

  • seems to be fine, and we are still not getting pregnant.

  • IR: So you really need the

  • fallopian tubes to be open.

  • SP: Oh, can you ovulate even if the fallopian tubes are not open? IR: Yes.

  • So the fallopian tubes need to be open because the eggs come from

  • the ovary,

  • fertilization occurs in the fallopian tube, and then the embryo

  • goes down

  • to the uterus.

  • And if the fallopian tubes are blocked,

  • you can ovulate, but you can't fertilize the egg.

  • SP: Where does the egg go then, if they are blocked? IR: It just disintegrates.

  • SP: and then that means sperm can never get to the egg. IR: Right.

  • SP: What causes blocked fallopian tubes?

  • IR: There are a number of causes - a woman could have a ruptured appendix,

  • and that infection can cause

  • a blockage of her

  • fallopian tubes. She could have a

  • sexually transmitted disease,

  • such as, chlamydia or gonorrhea

  • and that could block a tube.

  • She could have endometriosis, and have a blockage as a result of that.

  • So it is very important to find out whether the fallopian tubes are open

  • because otherwise

  • you can't get pregnant on your own.

  • SP: What if you find that they are blocked? Then what do you do?

  • IR: In some cases you can open them, but in the majority

  • of the cases you undergo in Vitro Fertilization

  • which can bypass the fallopian tube so we

  • remove the eggs,

  • fertilize them in a dish, and then we put them into the uterus. So, we bypass

  • the fallopian tubes.

  • SP: Okay, so what else could be a problem then?

  • IR: Those are the major ones, those are the ones that

  • we call 'Deal Breakers' because

  • you know, if you don't have sperm, if you don't ovulate,

  • and if you have blocked fallopian tubes - those are

  • serious problems.

  • SP: How about - Say, I am 45 now.

  • I have been ovulating, I am 45, I look very youthful, I have kept myself in

  • great shape,

  • I've got a younger partner, so his sperm is fine,

  • we know the fallopian tubes [are fine] -

  • Why would not be getting pregnant then?

  • IR: Well because we know that

  • it takes

  • more eggs

  • or more cycles, or more trying

  • to actually get to the one egg that's going to be normal

  • because with age the percentage of eggs

  • that are affected by

  • all kinds of abnormalities goes up.

  • SP: But I am so youthful!

  • i mean I can do a triathlon, I can do - I mean why would my eggs i didn't even any why would why eighties

  • not be as youthful as I appear to be, even though I am thirty-five?

  • IR: We're not sure but we think it was an

  • evolutionary advantage

  • not to have babies in our forties and fifties. So-

  • SP: Are you saying that even if I can keep my biceps relatively good, there is

  • no exercise to keep these eggs young?

  • IR: No,

  • the only thing you can do is not smoke cigarettes

  • and not get radiation or chemotherapy to your ovaries. Those things ACCELERATE the loss of

  • fertility

  • but otherwise, your ovaries are on their own time clock.

  • SP: They sort of every year get older, no matter what's going on with my life.

  • IR: Right. SP: Okay, so then that

  • probably would be a key thing that you would ask too, if I come in - is my age.

  • IR: Yes.

  • SP: And if I'm 50?

  • Can I still get pregnant then?

  • IR: If a woman is 50,

  • her uterus may be able to carry a pregnancy

  • but the likelihood that she would be able to get pregnant with her own eggs is very remote -

  • less than one in a thousand -

  • so in that case some women will carry

  • either

  • an embryo that was made from a donated egg

  • or a donated embryo, from a younger woman.

  • And that is often a very

  • good solution

  • for a couple where the woman is already

  • past fertility.

  • SP: When you say "past fertility,"

  • what age are we sort of looking at?

  • IR: Well, at 38 it is 50/50.

  • and at 47 it is basically 100%.

  • SP: So if I want to get pregnant without using a donated egg, then I really should do

  • it before 38.

  • IR: Yup -

  • to start trying

  • and some women who

  • want to postpone childbearing, will either freeze their eggs or freeze embryos

  • for later use.

Hi, my name is Sue Pascoe and I am a staff writer at the Palisadian Post, which

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