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  • - [Narrator] Humans need dentists. It's a fact.

  • In 2017 alone,

  • Americans spent $129 billion on dental visits,

  • and an estimated 90% of adults in the US have fillings.

  • But many animals don't have this problem

  • because they can regrow their teeth,

  • replacing old damaged ones with brand new pearly whites.

  • Wouldn't it be great if you could do that?

  • Well, there's actually an important trade-off

  • for this nuisance.

  • Only a handful of mammals can regrow teeth multiple times

  • compared to the 50,000 species of reptiles and fish.

  • Take geckos for example.

  • They replace all 100 or so teeth every three to four months,

  • and since geckos can live for six to 10 years,

  • they'll grow anywhere from 1,800

  • to 4,000 teeth in a lifetime.

  • That's all thanks to a special type of cell in their gums

  • called stem cells.

  • Stem cells are handy because they can morph into different

  • cells when needed,

  • like tooth stem cells to build new teeth.

  • Humans have these stem cells when we're younger,

  • but after our adult teeth grow in,

  • the stem cells die and disappear.

  • To understand why, let's take a journey back in time

  • to about 320 million years ago when mammals

  • and reptiles split off.

  • In addition to many obvious differences,

  • another change that eventually emerged was tooth shape.

  • Reptiles, for example, are what's called generalists,

  • meaning they eat the animals they can get their teeth on.

  • And for that, they needed teeth with the same size and shape

  • to keep prey from escaping their mouths.

  • Mammals, on the other hand, developed more specific diets,

  • like grazers who only eat grass and hunters who rip flesh

  • from their kills.

  • As a result, mammals evolved different-shaped teeth

  • for different purposes.

  • And it's this difference that could also explain

  • why mammals can't regrow more teeth.

  • Now, let's say you could regrow your molars multiple times, for example.

  • It's important that the top and bottom sets match up.

  • Otherwise, they can't grind food as efficiently.

  • That sounds good in principle, but with each new set,

  • there's a risk that the regrown teeth won't line up.

  • So the leading theory is that adult humans can't regrow

  • our teeth because it was better for survival

  • to only grow one well-aligned adult set.

  • However, if you still wish you could regrow a tooth,

  • there may be a way in the future.

  • Using lasers and drugs, scientists have helped rats and mice

  • regrow damaged tissue in cavity-ridden teeth

  • with the idea that if you could regrow tooth tissue,

  • you could eventually regrow entire teeth,

  • though no human testing has been done on that yet.

  • So keep flossing and keep seeing your dentist.

  • At least for now.

- [Narrator] Humans need dentists. It's a fact.

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