Subtitles section Play video Print subtitles For most people when they drink alcohol it can make them feel more confident and comfortable But for me, drinking makes me feel less confident and uncomfortable That's because thanks to my DNA... alcohol makes my skin turn red It's called the Asian Flush And it affects about 36% of North East Asians with higher rates among Asian Americans. I guess we should probably show you what it looks like "For Science!" "If I know that I'm gonna need to take pictures that I'll drink less until these pictures are over and then I'll go back to normal pace" People tend to assume that a red face means that we're drunk but that's a myth These are completely separate processes Facial flushing whether from embarrassment, or exercise, or alcohol... It happens when the blood vessels under the surface of the skin dilate. And in the case of Asian flush, this is part of an immune response The body is detecting a threat The threat isn't the alcohol itself but a substance that our livers produce while breaking down alcohol "For me at least, the warmth starts in my chest and then it moves its way up." "My cheeks are warm, my ears are warm..." "It's weird. It's like my eyes are almost puffy" "Ahh I do feel like they got puffy..." When people drink ethanol, that's the chemical name for booze. The liver gets rid of it using two main enzymes. The first reacts with the ethanol molecule to produce a substance called acetaldehyde. And the second quickly turns acetaldehyde into acetate, which is similar to vinegar and easy for the body to eliminate. It's that second enzyme that really screws things up for people with Asian flush. If you look inside our DNA you'll find that the gene providing the instructions for that enzyme was tweaked at some point in our history And that gene mutation produces an inactive enzyme So when we drink our bodies accumulate acetaldehyde at a level about 6 times higher than normal people If acetaldehyde sounds familiar that maybe because it's similar to formaldehyde It's toxic That's why it triggers the immune responds And the red face is really the least of it After having that one beer I didn't feel tipsy at all, but my heart rate doubled My eyes were bloodshot, and within half hour I had a headache Even worse, acetaldehyde can cause cancer It's a problem because people can actually develop a tolerance to Asian flush and that allows them to drink pretty heavily Studies have shown that heavy drinking raises the risk of esophageal cancer for everyone but especially for people with Asian flush So it's potentially problematic that alcohol consumption in Asia has been increasing especially in China So if you have an Asian flush, be careful Your body is freaking out for a reason And if you don't flush...just don't expect us to keep up with you And also... "You don't have to bring it up every time...like, yes I know that you're red..." "I know this, thanks, awesome..."
B1 US Vox flush asian alcohol drink enzyme Asian flush, explained 17126 1071 Sabrina Hsu posted on 2016/11/07 More Share Save Report Video vocabulary