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  • Japanese scientists have recently successfully turned mice translucent.

  • Hi there viewers, Julian here for DNews. Translucent animals are more common than you probably

  • think, in that they actually already exist.

  • Most of the naturally occurring ones are found in the deep ocean. There’s so little light

  • that reflecting any that does reach that far down can make them a tasty piece of deep sea

  • horror sushi. So a lot of deep sea critters are see-through to avoid that. You might notice

  • a lot of them are red or a transparent pink too, because red light’s long wavelength

  • means it has low energy and doesn’t penetrate water well. Thus animals that only reflect

  • red light are essentially invisible down there. Isn’t science neat?

  • Up here there’s not much point in having transparent skin. There’s so much light

  • that being a gooey see-through blob of floating bones and organs is going to be a bit more

  • noticeable than being the same color as your surrounds, so it doesn’t really make sense.

  • Of course scientists aren’t hampered by your preciouslogicand have bred a

  • few frogs and goldfish to have see through skin. Researchers in Japan took the most pale

  • ones they could find and kept breeding them together.

  • The goal is to be able to observe the internal organs while the animal is alive, making it

  • easier to keep track of tumor growth and how they react to chemicals. This for me raises

  • an important philosophical question. No it’s not, “should scientists play god?” I want

  • to know what you call a see through goldfish.

  • But now there’s a way to turn the skin, brain, lungs, the whole shebang except the

  • bones clear. A team at the RIKEN quantitative biology center in Osaka pulled off the trick

  • on mice by flushing out their circulatory systems with saline and then pumping a chemical

  • through them for 2 weeks.

  • The chemical removes heme from the mice. Heme is found in most tissue and is theheme

  • part of hemoglobin, it’s the compound in blood that binds to oxygen and also gives

  • it its red tint. Fun fact: your blood is always red, regardless of whether or not it has oxygen.

  • Remember what I said about red light not being able to penetrate well because of it’s low

  • energy? That’s why your veins look blue under your skin.

  • Totally transparent mice make it possible to see the cellular networks inside tissue.

  • Hiroki Ueda, who led the team, hopes it can be used to gain a better understanding of

  • cancer or autoimmune diseases by being able to observe how they develop without having

  • to dissect the mice.

  • As it so often goes though, the mice don’t get off easy. Being stripped of blood and

  • then heme entirely is pretty much game over. But I for one am resting easier knowing that

  • there’s no nightmare fuel jell-o mice running around with the chance to escape and breed

  • and form an invisible army of horror and cheese theft.

  • If you want to learn another way to turn yourself invisible while keeping all your blood in

  • you, Amy’s got a video on that over here.

  • If youve got a story of a time science did something awesome for lab mice, I want

  • to hear about it in the comments. I’m not a vegetarian or anything, but I can only read

  • so many stories about lab mice before I need a pick me up. Until then, I’ll see you next

  • time on DNews.

Japanese scientists have recently successfully turned mice translucent.

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