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  • I love that feeling when it's the beginning of fall and it's 55 degrees outside

  • and it's finally cold enough to wear my favorite winter sweater and jacket and beanie and gloves.

  • And I drink pumpkin spice lattes to stay warm.

  • But I also love the feeling when it's the middle of winter and out of nowhere it's 55 degrees.

  • So I leave my parka home and go outside in my shorts and t-shirt

  • and I feel the warmth of the sun on my skin.

  • And I consider going to the beach to tan because it's so warm.

  • The temperature is the same, but my reaction to it is vastly different.

  • Part of the reason why is that there's more of a substance in my body in January as compared to September.

  • It's the same substance that allows kids and teens to handle the cold weather better than adults.

  • When you're hot, you sweat.

  • When you're cold, you shiver.

  • But just before you start to shiver, your body actually does something else.

  • It starts to burn fat.

  • But not the fat we usually think of.

  • There are two categories of fat that we like to think about.

  • There's the white fat.

  • White fat is the one that we tend to just think of as "fat".

  • It's called white because it looks white.

  • White fat exists all throughout the body,

  • cushioning our bones and organs.

  • That's Dr. Aaron Cypess, by the way.

  • White fat cells have many functions.

  • One of the most important being that they're the body's primary energy source.

  • Every single day we are using the fuel that's inside the white fat cells.

  • But there's another type of fat that has a totally different function:

  • Brown fat.

  • These cells are much smaller,

  • and because of that, resemble muscle more than fat.

  • Instead of one large lipid droplet in a white fat cell,

  • the brown fat cell is one tightly packed bag of mitochondria.

  • This is what gives it its brown appearance.

  • And if you remember anything from high school biology class,

  • you know that the mitochondria are the powerhouse of the cell.

  • Brown fat, instead of serving as an energy reserve for organs throughout the body to burn,

  • uses its power to burn energy on its own.

  • And unlike white fat, it's only located in a few tactically positioned areas.

  • It is in the neck, the shoulders, in the upper arms.

  • It's down the spine and then some places within the belly.

  • Lots of overlap with major blood vessels

  • because warming the blood effectively warms the whole body.

  • The brown fat around the neck vessels heats up the blood, goes to the brain.

  • That's good.

  • The brown fat depots in the shoulders.

  • That blood, once it's been heated by the brown fat goes rightvery quickly, into the heart

  • and then can get pumped to the rest of the body.

  • And that's the first line of defense against the cold.

  • If it's not enough to raise the body temperature sufficiently...

  • then the body shivers.

  • But one of the craziest things that I learned while researching this story is that...

  • babies can't shiver.

  • When babies are born, they do not have the muscle mass

  • and perhaps not even so much of the coordination with the brain and the muscle to shiver effectively.

  • So they need other ways of generating heat,

  • and brown fat is part of that.

  • Babies are born with a lot of brown fat.

  • According to the Cleveland Clinic,

  • about 2 to 5% of a baby's body weight is made up of this stuff.

  • It's necessary for our survival.

  • The peak age for brown fat actually seems to be in the teen years,

  • which explains why a lot of the guys in my high school wore shorts in the winter.

  • But as we get older, our body makes less of it.

  • And this could give us some insight into why kids seem to run hot

  • and our parents or grandparents seem to run cold.

  • Older people, they certainly have much less brown fat in terms of absolute and relative amounts.

  • There's also less muscle,

  • which is also important for generating heat.

  • The similarities between brown fat and muscle don't end there, though.

  • If you work your brown fat out, it also increases volume.

  • And the way you do this is by exposing yourself to the cold for extended periods of time

  • as this 2014 study shows.

  • Look at how much more brown fat these men from Maryland had after a month of exposure to cold temperatures.

  • And look how much less they had when exposed to warm temperatures.

  • Which gives us some insight into why 55 degrees in the winter can feel so much warmer than 55 degrees in the fall.

  • Brown fat doesn't just keep you warm, though.

  • Scientists have figured out that having more of it correlates to lower risk of diabetes and heart disease.

  • Studying the effects of brown fat using cold exposure is challenging, though.

  • One challenge is that it's hard to dose cold.

  • How much... I gave you this amount of cold,

  • I mean, you know the temperature,

  • but it's hard to know what you're doing

  • and therefore it's very hard to design a study where it's reproducible.

  • So instead,

  • they're trying to activate brown fat with medicine to study how burning it affects us biologically.

  • A medication called Mirabegron,

  • which is approved to treat overactive bladder,

  • was able to activate the brown fat in a way that was very similar to the effectiveness of the cold exposure.

  • There's a lot we still don't know about brown fat,

  • but we do know that our bodies use it to adapt to cold weather.

  • And when a kid doesn't want to put a coat on in the winter,

  • it's not necessarily that they're just stubborn.

  • It might just be because they have a little more of something in their body than you do.

I love that feeling when it's the beginning of fall and it's 55 degrees outside

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