It's a major milestone in the race to control the faster spreading variants off the virus.

Ministers are hoping to avoid yet another lock down by protecting the most vulnerable groups on the plan is to offer vaccines to 15 million people those aged 70 and over healthcare workers, people who need to shield by mid February.

In the meantime, experts say that the number of deaths will remain significant as infection levels they say are still alarmingly high.

Our political editor, Laura Ginsburg, has the latest sleeves up syringes ready vaccine in Army medics filling this church hall in Kingsford.

But they used to be bingo nights on dog training.

They've done 400 by lunchtime.

No hanging about.

Obviously, a lot of people are shocked that were here.

But then there also so thankful that we're here and it's just nice to be to just feel like appreciated.

They've literally come out of their house just for this vaccination.

They have literally turned around and said look, we can't thank you enough, and I can't tell you how much that resonates with each and every one of us.

Now the whole country has hit the 10 million mark.

We have today passed the milestone of 10 million vaccinations in the United Kingdom, including almost 90% of those aged 75 over in England.

Whether a church hold a town hall, a temple or a car park at a leisure center, their arm, or and more places right around the country where the vaccine is on offer, helping to loosen the grip the pandemic has had on our country for such a long time.

But the vaccine program, astonishing though it is, is not a route out on its own.

You sure the vaccines work on all the various prime minister?

He's accused of leaving a gap where Mawr dangerous versions of the disease could creep in.

Boris Johnson promised travelers arriving from 30 at risk countries would have to stay in hotels, airports for 10 days, but there's no date for when that will start on.

Labor wants every country on the list with new variants in the country.

Are schools shut on our Borders Air open 21,000 people are coming into this country every day.

The prime minister's new border arrangements are still weeks away from being implemented.

This queue in a London suburb isn't for the vaccine, but extra testing to clamp down on the new variant of the disease from South Africa.

That's already here in the government admitted today.

At least 20,000 people instructed toe isolate with the disease aren't doing so.

Therese came out for the first time for many months for her vaccine, but understands why others might break the rules.

There are people still going to work because they need the money.

They're not doing it to deliberately see I don't care.

And in lock down, 28 year old knish has become the breadwinner.

But he reckons it's hard to force people to stay at home.

I think the majority of people will not self isolate because off locked down fatigue, Andi on also I would say not clear messaging from the government.

Was it clear today?

Can you give a firm date for when hotel quarantine will start on?

Will you offer Mawr help for people who just can't afford toe isolate If not, aren't you leaving two big holes in our defenses?

We have among the toughest border regimes now anywhere in the world where restricting as much as we can any risk of importing new infection into this into this country without totally secluding the UK economy.

With NHS testing traces reaching 90% of contacts, Andi Andi the vast majority of them are doing the right thing.

Prime Minister did confirm he wants England at least to leave.

Lock down is one, even if the rest of the UK might follow different timetables.

But while there's jubilation at the vaccine, there are still obstacles ahead.

It's too early to take a break.

Laura could spark BBC News.

Now the farmer giant AstraZeneca and Oxford University say they plan to have a next generation Covic vaccine ready for the autumn.

The new job will help to give people protection against some of the latest variants discovered recently.

The health secretary, Matt Hancock, said the latest research indicating that the Oxford AstraZeneca vaccine might reduce the spread of the virus was superb news.

Our medical editor, Fergus Walsh, has more details.

The scientists at Oxford who created the AstraZeneca vaccine are continually monitoring how coronavirus is evolving.

The current vaccine is thought to give good protection against new variants, but they're working on tweaking the jab to make it future proof that Theo scientist, who's leading the research, says it's relatively simple to redesign the vaccine.

It's not difficult to put a different anti genic insert into the vaccine, so we don't want Thio panic and say that we we must have a new version of the vaccine now.

But on the other hand, we are getting prepared so that if it turns out we do need a new version, it will be ready to start using it.

So it's just going to be a sharp scratch.

Those on the Oxford vaccine trials were shown to have 76% protection from a single dose, which lasted three months.

Rising toe 82% protection.

With the second shot, you're doing swabs every week.

A home.

It's also the first time a co VID vaccine has been shown to reduce transmission of coronavirus.

Those immunized were much less likely to test positive for infection, cutting the risk of them passing the virus on to others.

That's the vaccine.

But what about those who actually had co vid.

They want to know how long they may be protected against subsequent infection.

A study involving nearly 20,000 volunteers may provide at least part of the answer.

Like the other participants, I was asked to send off a few drops of my blood every month to a lab.

Scientists at UK Bio Bank found that 88% of participants nearly nine in 10 who started off with antibodies still had them six months later.

I think these funny is a really good news because it does suggest that people who have been infected with the virus may have some degree of protection against another infection for some considerable time.

I think what we'd really like to know next is how long does this doesn't this natural immunity last four beyond six months?

Scientists think vaccines are likely to offer much stronger protection than natural infection.

So a key message is to get immunized even if you've already had co vid to boost your immunity on, maybe protect others Fergus or BBC news.

So let's take a look.

Then, at the latest official figures, they show a continuing fall in new cases of Corona virus.

There were 19,202 new infections recorded in the latest 24 hour period, which means that on average, the number of new cases reported per day in the past week is 22,396 across the UK an average of 32,851 people were in hospital with coronavirus over the seven days to Monday, including suspected cases in Wales, 1322 deaths were reported.

That's people who died within 28 days off a positive covert test.

On average, in the past week, 1000 and 64 deaths were announced every day.

Total number of deaths so far across the UK is 109,335 on.

Let's look at the vaccination roller now then, just these figures.

374,756 people have had their first dose of one of the three approved vaccines in the latest 24 hour period on as we've heard, that takes the overall number of people for their first job to 10,021,471.

Let's have a word tonight again with our health editor, Hugh Pym.

Lots of people looking at these very impressive vaccination figures you and then wondering, Well, does that mean there's a change of calculation around when lock down might be east?

We're here.

There's certainly more optimistic tone to this media briefing than some we've seen in recent weeks.

The prime minister talked about signs of hope, although infection levels, he said, were very high on.

Professor Chris Witty, the UK government's chief medical adviser, went further than before to say We were passed the peak of this recent surge, he said.

All the key numbers on the graphs were coming down.

That's case numbers, numbers in hospitals.

Andi deaths.

So the questions were being asked at the briefing.

What did this mean for restrictions?

But the prime minister was sticking very much to his previous line, which is that you need to get ALS.

The key priority groups.

The top four groups seventies and over, vaccinated by the middle off this month and then wait three weeks till full immunity had Bean built up for as much as possible to be absolutely certain, and only then on March the eighth to open up schools in England and possibly consider other restrictions being used as well.

That's even though Scotland's indicated it will start opening up schools later this month on the Welsh government is considering it as well.

So sticking to that pretty cautious line on one clue was given by Chris Witty.

When asked why this was being adopted.

This sort of line, he said with A With these variants, it only takes cases to go up a bit for the NHS to get into trouble very quickly again.

Many thanks Once again, Hugh Pym, I have 30.