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  • HARVARD RESEARCHERS BELIEVE THAT THEY CAN REVERSE DNA AGING.

  • WELL AT LEAST THEY PROVEN THAT THEY CAN REVERSE DNA AGING

  • IN MY SENSING THEY WILL BE TESTING THIS METHOD ON

  • HUMANS AND IT IS A PRETTY BIG DEAL.

  • THEY FOCUSED ON AN INTRIGUING COMPOUND WITH ANTIAGING

  • PROPERTIES CALLED NAD+.

  • IT'S BEEN KNOWN THAT YOUNGER MICE HAD MORE OF IT THAN

  • OLDER MICE AND BACK IN 2013, THE RESEARCHERS FOUND THAT WHEN

  • THEY BOOSTED THE NAD+ LEVELS IN OLDER MICE THEY LOOKED,

  • BIOLOGICALLY, LIKE MUCH YOUNGER ANIMALS.

  • BANANAS.

  • THEY COULDN'T EVEN DIFFERENTIATE BETWEEN THE

  • OLDER MICE IN THE YOUNGER MICE AFTER THEY STARTED GIVING

  • THE OLDER MICE THIS COMPOUND.

  • SINCLAIR, THAT'S ACTUALLY DOCTOR DAVID SINCLAIR FROM

  • HARVARD, PUT DROPS OF NAD+ INTO THE WATER OF A GROUP

  • OF MICE AND WITHIN A COUPLE OF HOURS, THEIR NAD+ LEVELS

  • STARTED TO RISE THAT WITHIN THE FIRST WEEK, THE SCIENTISTS SAW

  • OBVIOUS AGE REVERSAL IN MUSCLE AND IMPROVEMENTS IN DNA REPAIR.

  • THAT'S IT, WEíRE DONE.

  • THIS IS THE MOST IMPORTANT STORY THAT WE HAVE EVER COVERED.

  • NOTHING ELSE MATTERS AT THE

  • I AGREE WITH HER.

  • THIS IS FREAKING PHENOMENAL AND I'M SUPER EXCITED THAT

  • I WANT TO GET MY HANDS ON NAD+ IMMEDIATELY.

  • I'M LOOKING AT CENK UYGUR'S NOTES AND THEYíRE

  • HIGHLIGHTED THROUGH AND THROUGH.

  • THE ENTIRE ARTICLE IS HIGHLIGHTED THROUGH AND

  • THROUGH.

  • YOU DIDN'T HAVE THIS LEVEL OF DETAIL -

  • I DONíT KNOW IF YOU CAN SEE ALL THE HIGHLIGHTS.

  • I GOT EXCITED I'M NOT MESSING AROUND WITH THAT.

  • YOU HAVE TO STOP EATING NOW IF YOU WANT TO REMAIN

  • HEALTHY REGARDLESS OF HOW YOUNG YOU BUT.

  • NOT NECESSARILY MAN, AND THEN HAD PLEASANT EVERYTHING IS

  • GOING TO BE OKAY TO LET ME QUOTE THE GOT THE DOCTOR AGAIN.

  • WE CAN'T TELL THE DIFFERENCE BETWEEN TISSUES FROM AN OLD

  • MOUSE THAT IS TWO YEARS OLD VERSUS A YOUNG MOUTH THAT IS

  • 3 TO 4 MONTHS OLD.

  • GOOD NIGHT, IRENE.

  • OR NO GOOD NIGHTS.

  • WEíRE GOING TO GET YOUNGER AND YOUNGER

  • AND YOUNGER.

  • HIT ME WITH NAD+.

  • THE BEST PART IS YOU DON'T HAVE TO DO ANYTHING INVASIVE.

  • YOU JUST HAVE TO CONSUME IT.

  • BUT, IF THEY DID A TEST ON HUMANS WITH WHICH THEY PLAN

  • ON DOING.

  • THEY'RE GOING TO DO THE FIRST TEST ON 25 HUMANS TO SEE WHETHER

  • OR NOT IT HAS THE SAME IMPACT ON THEM LIKE IT HAS ON THE

  • MICE, BUT THE MICE JUST DRINK THAT SHIT UP.

  • YOU KNOW?

  • THEY DIDNíT HAVE TO DO ANYTHING CRAZY.

  • NO IMPLANTS OR INJECTING ANYTHING.

  • THEY INGESTED IT.

  • WE WOULD JUST HAVE TO INGEST IT.

  • IT IS THE MAGIC PILL.

  • IT'S ALSO THE COMPOUND FOUND IN MICRO-DOSES AND

  • BROCCOLI, AVOCADO, CUCUMBERS, THINGS THAT I EAT A LOT

  • ACTUALLY, BUT WHAT I WAS GOING TO SAY THAT'S

  • IT'S NOT WORKING ON YOU.

  • WELL, DO YOU HEAR THAT?

  • HERE'S WHAT I'M GOING TO

  • SAY ñ IS NO ONE TERRIFIED BY THIS?

  • THIS IS EVERY PLOT POINT TO EVERY ZOMBIE MOVIE EVER.

  • THIS IS EXACTLY HOW ZOMBIE MOVIE START.

  • THIS IS HOW YOU START.

  • BLACK HELICOPTERS, ZOMBIES, I'M

  • GLAD THAT THEY'RE DOING THE METRO BIOTECH IS IN BOSTON

  • SO AT LEAST WILL BE CONTAINED IN THE AREA.

  • WHAT MAKES YOU THINK IT WILL BE CONTAINED?

  • REMEMBER DEATH BECOMES HER?

  • 25 PEOPLE ARE GOING TO TURN INTO ZOMBIES.

  • ARE GOING TO BE MISSING.

  • BUT LUCKILY BECAUSE IT'S IN THE BOSTON AREA THEY WILL

  • HANDLE IT QUICKLY BECAUSE EVERYONE KNOWS BOSTONIANS

  • ARE VERY AGGRESSIVE ESPECIALLY AROUND FOOTBALL SEASON.

  • I JUST GENERALIZED.

  • WEíLL GET BACK TO THE STORY.

  • THE

  • WAY WE AGE IS DNA COPIES ITSELF AND SOMETIMES WHEN IT COPIES

  • ITSELF IT'LL COPY A NOT SO PERFECT VERSION AND THAT IS

  • WHAT KIND OF LEADS TO AGING.

  • THAT IS AN OVERLY SIMPLISTIC WAY OF DESCRIBING AND

  • ESSENTIALLY WHAT HAPPENS IS YOUR BODY NEEDS THESE DNA REPAIR

  • COMPOUNDS IN ORDER TO REPAIR ITSELF IN A MORE EFFECTIVE

  • WAY, AND A BETTER WAY, AND A MORE PERFECT WAY I GUESS.

  • THAT IS WHAT PREVENTS AGING.

  • THAT IS WHAT THIS IS, THEN ADD PLUS IS A DNA REPAIR COMPOUND.

  • WITH HUMANS, THE REPAIR COMPOUND IS CONSUMMATE A LITTLE DIFFERENT

  • THAT I CAN'T PRONOUNCE IT, BUT THE SHORT VERSION IS MNM.

  • THE NATURALLY OCCURRING COMPOUND FOUND IN SMALL AMOUNTS

  • IN FOODS LIKE BROCCOLI, CUCUMBER, AVOCADO, EDAMAME.

  • I JUST WANT

  • THE RECORD I'M A BIG FAN OF AVOCADO TOAST.

  • I EAT A LOT OF

  • IT.

  • I FEEL VINDICATED ABOUT THAT.

  • CAN I JUST SAY ONE THING.

  • CAN Y'ALL CHECK TO SEE IF

  • Y'ALL CAN CURE THE RATS FROM CANCER?

  • WHY ARE WE SO

  • PREOCCUPIED WITH YOUTH IN AMERICA?

  • YOU CAN WALK AROUND WITH AN OLD SOUL.

  • IT DOESN'T MATTER IF YOUR FACE DOESN'T MOVE.

  • IT'S OKAY

  • TO GET OLDER.

  • WHY ARE WE SO PREOCCUPIED WITH NOT GETTING OLDER?

  • IT'S OKAY.

  • SO THAT'S A LARRY KING.

  • IT'S SO MUCH PRESSURE ON WOMEN ALL THE TIME WITH THIS.

  • STOP IT.

  • WE CAN BE INVESTING THIS TIME INTO SOMETHING ELSE.

  • IT'S NOT JUST ABOUT LOOKS, WHICH I WILL ADMIT, THAT'S

  • THE PART OF IT THAT I CARE ABOUT THE MOST, BUT IT'S NOT JUST

  • ABOUT THAT BECAUSE IT HELPS REBUILD HEALTHY TISSUE.

  • ALSO, YOU BROUGHT UP CANCER AND I'M GLAD THAT YOU DID BECAUSE

  • THIS COULD HAVE HUGE BENEFITS OF FOUR CANCER PATIENTS.

  • APPARENTLY, SCIENTISTS HAVE HARNESS THIS TO TARGET CANCER

  • CELLS, CANCER DRUG CALLED PAR PA INHIBITORS WHICH ARE PRESCRIBED

  • FOR BREAST CANCER INTERFERE WITH PAR P'S ABILITY TO REPAIR DNA IN

  • THE TUMOR WHICH ULTIMATELY LEADS TO THEIR DEMISE BUT NOW

  • PEOPLE WHO TAKE THE DRUG RESPOND WELL TO WAY AND MANIPULATE

  • THAT PLUS LEVELS MIGHT BE ONE WAY TO ENHANCE THE RESPONSE.

  • IT COULD HELP CANCER PATIENTS AS WELL.

  • LET ME TRY TO EXPLAIN, AGAIN ALL OF THIS IS A LITTLE

  • OVERSIMPLISTIC.

  • NOT PLUS, WHEN THEIR LEVELS ARE HIGHER THAN PAR P1 IS ACTIVATED

  • AND CAN REPAIR THE DNA.

  • IN THE CASE OF CANCER, YOU DON'T WANT TO REPAIR THE DNA OF

  • THE CANCER CELLS SO THEY ACTUALLY LOWER THE PART AND

  • THAT WINDS UP KILLING THE CANCER.

  • IN THE CASE OF REVIVING YOUR YOUTH, YOU WANT THE PART TO BE

  • HIGH ANYONE THAT PLUS LEVELS TO BE, BECAUSE WHEN THAT PLUS

  • LEVELS ARE HIGH THAN PART ONE IS ACTIVATED AND THEN YOUR DNA

  • HEELS AND YOU BECOME YOUNGER.

  • THE BOTTOM LINE IS WE'RE NOT GOING TO DIE.

  • I

  • AM NOT PLAYING.

  • LET ME GET REAL, I KNOW IT SOUNDS A LITTLE LIKE THE ZOMBIE

  • THING THAT HOSPICE TALKING ABOUT, AND I AM NOT SAYING THEY

  • IF YOU HAVE IN A CAR ACCIDENT, BEGIN A CAR ACCIDENT YOUR DEAD.

  • OF COURSE.

  • THIS DOESN'T MAGICALLY UNDEAD YOU.

  • YOU ARE NICELY GOING TO HAVE ZOMBIES.

  • THIS IS HOWEVER A TIME, AND EVERY SINGLE MOVIE

  • LET ME TALK ABOUT HOW IT'S GOING TO BE REAL THOUGH.

  • WE ARE ON THE EDGE OF SCIENTIFIC BREAKTHROUGHS THAT ARE

  • GOING TO CHANGE THE ENTIRE WORLD.

  • THE NUMBER ONE PROBLEM IS, I TALK ABOUT ALL THE TIME ON

  • THE SHOW WHETHER IT'S POLITICS OR ANYTHING ELSE'S PEOPLE

  • CANNOT SEE OUTSIDE OF THEIR OWN PERSPECTIVE.

  • IN OUR LIFETIMES, WE'VE EVER SEEN IS THIS.

  • YOU AGE, YOU GET OLDER, YOU CANíT MANIPULATE YOUR GENES, ETC.

  • WE ARE ABOUT TO MANIPULATE THE GENES.

  • WE ARE ABOUT TO MANIPULATE THE DNA.

  • ITíS GOING TO AFFECT

  • PEOPLE THAT ARE ALIVE.

  • ITíS GOING TO AFFECT BABIES EVEN

  • MORE BECAUSE WE CAN CHANGE THE DNA WITHIN THE WOMB.

  • THAT IS NOW BORDERLINE EASY.

  • I'VE BEEN TALKING ABOUT THIS FOR LONG TIME AND HE THINK I AM

  • PLAYING OR EXAGGERATING.

  • I AM NOT THAT THEY ARE GOING TO BE SUPER BABIES.

  • THEY'RE GOING TO HAVE SLIGHTLY DIFFERENT GENES THAN US.

  • THEY COULD BE STRONGER, IT'S POSSIBLE THEY COULD BE SMARTER.

  • NOW YOU ARE TALKING ABOUT REAL SCIENCE-FICTION MOVIES BUT

  • ISN'T FICTION ANYMORE.

  • AND NOW, SCIENCE HAS ADVANCED SO MUCH THAT YOU MIGHT BE ABLE

  • TO MANIPULATE GENES OF A PERSON WHO IS ALREADY ALIVE TO

  • CURE THEM OF THINGS INCLUDING GROWING BACK LIMBS.

  • WE CAN'T UNDERSTAND IT.

  • ITíS A DIFFERENT PERSPECTIVE.

  • WE THINK THAT CAN'T BE TRUE, RIGHT?

  • SO WHEN WE LOOK AT THIS STUFF AND YOU THINK KNOW, YOU ARE

  • EXAGGERATING.

  • IT CAN'T REALLY MAKE YOU YOUNGER.

  • IT ALREADY MADE THE MICE YOUNGER.

  • IT ALREADY HAPPENED AND

  • THEYíRE TESTING IN HUMANS.

  • NOW 48 YEARS FROM NOW, NOT 88

  • YEARS FROM NOW, NOT A BRAVE NEW WORLD, TODAY.

  • IT DOESN'T MEAN THAT IT IS GOING TO HAPPEN IN 18

  • MONTHS AND ALL OF A SUDDEN WE'RE ALL IMMORTAL.

  • I ALSO WANT TO BRING DOWN YOUR EXPECTATIONS.

  • OF COURSE THIS IS DANGEROUS AND IMPORTANT STUFF.

  • THEY'RE GOING TO DO A TON OF TESTING BEFORE THEY ARE

  • LIKE HEY, EVERYBODY NOT PAUSE FOR EVERYONE.

  • YES WE ARE OVERSIMPLIFYING TO ALL THE THINGS ARE TRUE.

  • BUT IF NOT FOR OUR GENERATION, DEFINITELY FOR KIDS

  • GENERATION IS DEFINITELY GOING TO BE COMPLETELY DIFFERENT.

  • ONCE YOU START MESSING AROUND WITH THE GENES, ALL BETS

  • ARE OFF.

  • FOR THE GOOD AND PROBABLY ALSO FOR THE BAD.

HARVARD RESEARCHERS BELIEVE THAT THEY CAN REVERSE DNA AGING.

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