Name: Stop Buying Anti-Aging Creams — This One Food Rebuilds Skin From Within | Andrew Huberman
Uploaded: 2026-02-17T21:37:46.000Z
Duration: 16 min 56 s
Description: Thousands of YouTube videos with English-Chinese subtitles! Now you can learn to understand native speakers, expand your vocabulary, and improve your pronunciation...

Most people spend more money on what they put on their skin than what they put into their body.

Yet here is the biological Skin is not built from creams.

It is built from amino acids, essential fatty acids, vitamins and minerals delivered through your bloodstream.

In fact, the outermost layer of your skin is largely dead tissue.

No topical product can travel backward into your dermis and command your fibroblasts to manufacture structurally sound collagen in the way nutrient signaling from food can.

Here is what the research Collagen production declines steadily after your mid-20s.

By your 40s and 50s, the rate of collagen breakdown often outpaces synthesis.

What is happening in your body when this occurs is not cosmetic.

Fibroblast cells reduce output, oxidative stress increases chronic low level inflammation, accelerates matrix degradation.

The result is thinner skin, less elasticity, slower wound healing and the visible markers we call aging.

It responds to internal nutrient availability, inflammatory signaling and hormonal balance.

That means you can influence it from the inside out.

There is one specific food that delivers the precise building blocks required for collagen synthesis, glycine balance and dermal repair in a way most anti aging creams simply cannot replicate.

Today, we are going to break down the neuroscience and physiology behind skin aging the role of amino acids like glycine and proline, how inflammation silently erodes collagen, and

the simple protocol you can use daily to rebuild skin integrity from within.

By the end, you will understand not only what to eat, but

why it works at the cellular level and how to implement it in a way that supports your brain, joints and overall longevity alongside your skin.

Because anti aging is not about surface correction, collagen is often treated like a cosmetic buzzword.

But biologically, it is the most abundant structural protein in your body.

It makes up the scaffolding of your skin, tendons, ligaments and even parts of your vasculature.

If you zoom in at the microscopic level, collagen fibers form a woven mesh beneath the surface of your skin that gives it firmness, elasticity and resilience.

Studies published in journals such as the Journal of Investigative Dermatology demonstrate that fibroblast cells are responsible for synthes collagen inside the dermis.

These cells require specific amino acids, primarily glycine, proline and hydroxyproline.

Without an adequate supply of these building blocks, collagen production slows, not metaphorically, biochemically, what is happening in your body when collagen declines is straightforward but profound.

Fibroblasts reduce output matrix metalloproteinases.

Enzymes that break down collagen become more active under oxidative stress.

The result is a thinning extracellular matrix.

Visually, this shows up as fine lines, reduced elasticity and slower tissue repair.

Now here is the critical Most modern diets are rich in muscle meats such as chicken breast or steak.

These are high in methionine and other amino acids but relatively low in glycine.

Glycine is disproportionately concentrated in connective tissue, skin, tendons, ligaments and bone matrix.

Historically, humans consumed the entire animal, including these collagen rich tissues.

Have you ever noticed how people may consume high amounts of protein yet still experience joint discomfort, slow recovery or early skin thinning?

The one food that directly addresses this imbalance is bone broth made from slow simmered connective tissue and bones.

When prepared properly, bone broth releases collagen, gelatin, glycosaminoglycans and the specific amino acids required for dermal repair.

When you consume bone broth, digestive enzymes break collagen down into peptides and free amino acids.

Febroblasts detect amino acid availability when glycine and proline levels rise.

Collagen synthesis signaling pathways are stimulated, particularly in the presence of vitamin C, which acts as a necessary cofactor.

A simple tool to apply is consume one serving of high quality bone broth daily, ideally paired with a vitamin C source such as citrus or bell peppers.

This ensures that the collagen building process is not limited by micronutrient availability.

Collagen is the steel framework of your skin.

if there is no steel arriving at the construction site, no amount of polishing can rebuild the structure.

You can supply all the glycine and proline in the world, but

if chronic inflammation is elevated, your body activates enzymes that actively dismantle collagen fibers faster than you can rebuild them.

Here is what the research Ultraviolet exposure, poor sleep, high sugar intake and psychological stress increase inflammatory cytokines such as interleukin 6 and tumor necrosis factor alpha.

These molecules activate matrix metalloproteinases.

These enzymes degrade collagen in the dermal layer.

This process has been well documented in dermatological research, including studies observing photoage skin and inflammatory skin conditions.

What is happening in your body when this occurs is not just surface level damage.

Inflammatory signaling shifts your fibroblasts into a defensive state.

Instead of prioritizing growth and repair, they respond to perceived threat.

Oxidative stress increases reactive oxygen species damage cellular structures including lipid membranes and proteins.

Have you noticed how your skin looks duller after periods of poor sleep or psychological strain?

Cortisol, the primary stress hormone, when chronically elevated, impairs collagen synthesis and increases breakdown.

In other words, stress literally imprints on your skin.

This is why anti aging must be approached metabolically, not cosmetically.

Now here is where bone broth does something uniquely powerful beyond collagen peptides.

Properly prepared, bone broth contains glycine in meaningful amounts.

Glycine is not just a structural amino acid.

Research published in Nutritional Biochemistry Literature shows glycine can reduce inflammatory signaling and improve antioxidant capacity.

A simple tool to apply is replace one inflammatory food source per day with a collagen rich glycine supporting alternative.

For example, instead of a late evening sugary snack, consume a warm cup of bone broth.

This not only supplies building blocks, but may also support parasympathetic activation, promoting better sleep.

And better sleep further reduces inflammatory signaling.

Less inflammation means fewer matrix degrading enzymes.

Fewer degrading enzymes mean more net collagen retention.

More retention plus adequate building blocks equals structural improvement over time.

You can be eating what appears to be a high protein, health conscious diet and still be accelerating structural aging if the amino acid ratios are skewed.

Muscle meats such as chicken breast, turkey and lean beef are high in methionine.

Methionine is an essential amino acid and absolutely necessary for methylation, detoxification and cellular function.

However, when consumed in high amounts without adequate glycine, it increases the demand on metabolic pathways that regulate inflammation and oxidative balance.

Animal studies from institutions such as the University of Southern California have demonstrated that methionine restriction can extend lifespan in multiple species.

The mechanism appears related to reduced oxidative stress and improved metabolic signaling.

But the key insight is not that methionine is harmful.

Historically, humans consumed nose to tail.

That means not just muscle tissue, but skin, tendons, cartilage and bone matrix.

These tissues are disproportionately rich in glycine.

Glycine helps buffer the metabolic load created by methionine.

It also supports gluthionine production, one of the body's most powerful endogenous antioxidants.

What is happening in your body when glycine intake is chronically low is subtle but cumulative.

Oxidative stress rises, inflammatory tone increases.

Skin becomes thinner, less elastic, slower to heal.

Have you ever noticed individuals who eat large amounts of lean protein yet struggle with dry skin or joint discomfort?

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Stop Buying Anti-Aging Creams — This One Food Rebuilds Skin From Within | Andrew Huberman

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