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  • "Pesticides (DDT) and Alzheimer’s Disease"

  • Although there is a growing list of Alzheimer's disease

  • susceptibility genes, even if you put them all altogether,

  • they account for less than half of all Alzheimer's cases.

  • The single most compelling piece of data on the potential control

  • we have over the disease is the fact that if you have

  • identical twins, with the exact same genes, even if one gets

  • Alzheimer's the other usually does not.

  • So, we have to think about all the other

  • contributing factors beyond just genetics.

  • In my video on pesticides and cancer, I talked about this study.

  • There’s a list of chlorinated pesticides, including DDE

  • (a metabolite of DDT) that are classified by the EPA

  • as probable human carcinogens.

  • But in the study, blood levels of DDE and others were

  • associated not with increased cancer mortality,

  • but increased risk of other-cause mortality.

  • This led researchers to speculate it may be due to

  • an associated increased risk of diabetes or dementia.

  • I’ve talked previously about the diabetes link.

  • What about dementia?

  • Elevated Serum Pesticide Levels and Risk for Alzheimer Disease.”

  • A research team at Rutgers found significantly higher blood

  • levels of DDE in Alzheimer’s disease patients compared to controls,

  • and autopsy studies show blood levels

  • are a good proxy for brain levels.

  • Those with the highest levels were at about four times

  • the odds of being demented with Alzheimer's.

  • And in a petri dish, DDE increases amyloid precursor protein levels

  • in human brain cells, providing a potential mechanism.

  • Here are the levels of the sticky protein implicated in the

  • development of Alzheimer's disease before and after some DDE

  • is added, at the levels one finds circulating in highly exposed

  • individuals in the general population.

  • Put all these studies together, and there does indeed seem

  • to be a link, consistent with data showing about a doubling

  • of risk for developing dementia among

  • those acutely pesticide poisoned.

  • Among U.S. elders, DDT and its breakdown product DDE are also

  • associated with increased risk of cognitive decline in general.

  • DDT was extensively used in the United States

  • from the 1940s through the 1960s.

  • At its peak, we were churning out 180 million pounds a year.

  • And it’s still in our bodies to this day,

  • contaminating the bloodstreams of more than 90 percent of Americans,

  • and DDE, the pesticide linked to quadrupling the odds

  • of Alzheimer’s, were at the highest levels.

  • It’s still in our bodies because it’s still in the food supply.

  • In my last video on the topic, I noted that the levels of

  • DDT, DDE, and other banned pesticides and pollutants

  • were much lower in the breast milk from a vegetarian mother

  • compared to breast milk of her non-vegetarian sister.

  • And the largest difference was noted for DDE,

  • which was four times lower in the vegetarian sister.

  • This is what you see across the board for these kinds of pollutants.

  • Food samples were collected from supermarkets across the U.S.

  • Here’s what they found for dioxins and PCBs

  • in beef, chicken, pork, processed meat, eggs, fish,

  • all plant-foods put together, and dairy products.

  • These toxins build up the food chain; so, it makes sense that

  • the most contaminated foods are meat, fish, and dairy products.

  • 5 to 10 times higher levels in meat, eggs,

  • fish, and dairy than what they found in plant foods.

  • And unfortunately, cooking doesn’t destroy pollutants like DDE

  • in fact it may make them even more concentrated.

  • And this is for a pesticide that may increase the risk

  • of Alzheimer’s disease as much as if you carried

  • the so-called Alzheimer’s gene APOE e4.

"Pesticides (DDT) and Alzheimer’s Disease"

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