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  • Okay, I think it's time to turn down the morphine trip.

  • Welcome to watch Mojo.

  • And today we're counting down our picks for the top 10 drugs that exist in nature.

  • Autumn Ihsan was first discovered and successfully extracted in China.

  • In the letter, she said the medicine has helped China completely eradicate malaria for this list.

  • We're looking at some of the most surprising and best drugs and medicines formed from something in the natural world.

  • Do you have a favorite medicinal plant let us know below.

  • Are you in the market for a new smartwatch Check out, get mo hos list of recommendations in the description below.

  • And while you're there, don't forget to subscribe for the latest product reviews, unboxing and recommendations, number 10 gallon to mean in the 19 fifties, galante mean was first isolated from the bulb of the common snowdrop.

  • Also known as galante is novelas.

  • However, it's now been found in a range of snowdrop varieties.

  • This alkaloid substance was discovered to be able to cross the blood brain barrier as such.

  • It was realized that galante mean could impact people who have dementia and Alzheimer's galante mean cancer slow down the progression of these diseases by adding the decline of the brain's ability to transmit chemical messages.

  • Like with most treatments sadly there are side effects.

  • The most common are gastrointestinal issues such as nausea and diarrhea.

  • There's also research into how gallant amine could help autistic people while proteins in snowdrops are being examined as a possible treatment for HIV number nine, Ivermectin in 1978 step to mrs Obama Attila's an act of my seat, which is a type of bacteria was isolated at the Curtis Otto Institute from a soil sample in japan.

  • In 2015.

  • William C.

  • Campbell and Satoshi Omura were awarded a nobel prize in physiology or medicine due to their work in discovering ivermectin from the bacteria.

  • Ivermectin is a series of anti parasitic drugs and pesticides that combat parasitic worms and insect pests in both humans and and animals.

  • Some of the parasitic diseases that were significantly lowered from this discovery include river blindness and lymphatic filariasis.

  • One ivermectin medicine that became well known for misinformation was Ivor mexican.

  • It was wrongly believed to help with the effects of Covid 19, even though I never met him is a good drug for some parasites, it has not been shown in a well controlled placebo controlled trial to be effective in covid Number eight artemisinin to you.

  • Your received a nobel prize for her work in discovering artemisinin, a group of drugs that primarily combat malaria.

  • She found this in 1972 when she extracted the substance from the plant sweet warm wood, also known as artemisia annua, hence the name artemisinin for years, healers primarily in china have used sweet wormwood to help treat high fevers hemorrhoids and malaria, with the last one being something to was able to confirm.

  • While artemisinin is very effective in treating malaria the cost of creating it the effort required and the poor availability of sweet wormwood creates significant hurdles to overcome.

  • Number seven statins.

  • This class of drugs is known as lipid lowering medications, which means they reduce things like cholesterol in the bloodstream.

  • Primarily statins are used to reduce the risk and effects of heart disease like angina and possible heart attacks before statins came along.

  • Most high cholesterol patients were treated with a low fat diet which can be hit or miss with its effectiveness.

  • In the 19 seventies and eighties, an international group of scientists from Japan, the UK and the US were working on this issue, they discovered that certain fungi gave off an enzyme that would become the precursor for Staten production.

  • These fungi were penicillium, so Trina and asper Julius Darius statin medication was eventually approved in the US in 2001 is probably a little high, but you know, they have medicine for that night.

  • Number six Van Commission.

  • In 1953 american chemist Edmund Kornfeld was examining a soil sample that was collected by a missionary from the jungles of Borneo Kornfeld discovered the bacteria chemical autopsies orient Alice produced a compound capable of destroying penicillin resistant staphylococcus.

  • Originally given the dull name of compound oh 5865.

  • It was soon changed to vancomycin.

  • How vancomycin is notoriously hard to create as the compound needs to be purified an early non pure version, nicknamed Mississippi mud from its dark brown color had side effects of kidney damage and hearing loss.

  • As a result, vancomycin typically won't be the first medicine tried to cure bacterial infections like endocarditis and meningitis.

  • But pure versions have been shown to be effective.

  • Number five cyclists foreign.

  • While examining soil samples from Norway.

  • In 1971, scientists discovered the fungus to lipa Clady um inflate.

  • Um they soon saw it produced cyclosporin, which has an immuno suppressive effect.

  • That meant this medication could be vital for those requiring organ transplants to reduce the chance of rejection.

  • By 1980, cyclosporin, which is spelled numerous different ways, was used in trials for liver transplant patients before cyclists foreign patients had a survival rate of 50% after a year after using it.

  • That increased to 80% cyclists Boren was soon approved as a medicine in the US and it's even on the World Health Organization's list of essential medicines.

  • Other illnesses that cyclists foreign treats include Crohn's disease, psoriasis and rheumatoid arthritis.

  • Number four aspirin.

  • If you were to have any of the drugs mentioned in this list within your bathroom cabinet, it would likely be aspirin.

  • People didn't have headaches.

  • What would happen?

  • The aspirin industry also known as acetyl salicylic acid or a s a.

  • Its creation was inspired by the use of salicylic acid that's located in the bark and leaves of willow trees in this form.

  • This medicine has been treating people since the days of ancient Egypt when they chewed on the leaves and twigs of the tree.

  • In 18 53 french chemist Charles, Frederic.

  • Gerhardt combines sodium salicylic and acetyl chloride to create aspirin.

  • In its more modern form.

  • Aspirin traditionally treats pain, inflammation and fever, but it's also been used to treat other illnesses such as rheumatic fever, kawasaki disease and pericarditis.

  • But I did start taking baby aspirin to reduce my risk for heart attack.

  • That makes sense to keep an eye on it.

  • Number three, vin blasting and vin Christine, the Madagascar, periwinkle or Catherine.

  • These roses is a plant that produces two life saving treatments.

  • First, we have been blasting first isolated in 1958 It was discovered that it reduced the number of white blood cells within the body.

  • With that in mind.

  • Vin blasting has been used in chemotherapy to treat several types of cancers.

  • The other medication is been Christine, which was isolated in 1961.

  • After seeing a similar reaction to vin blasting.

  • Vin Christine Has also been used in chemotherapy to tackle various cancer forms.

  • In some cases it's increased the survival rates from 10% to 95%, interestingly, scientists were first looking at the periwinkle for combating diabetes and stumbled across this vital use by accident number two morphine.

  • The popover Som Paramore opium poppy has had a big impact on humans when it comes to pain morphine was first isolated by german pharmacist, Friedrich turner in 18 06, he spent nine years experimenting with it on himself, Three dogs, three young boys and a mouse.

  • He noted the potential danger of the drug during this.

  • Zero Turner also gave it its name inspired by the greek God of dreams, morpheus.

  • Another opiate from the same plant is codeine.

  • A weaker variant of morphine.

  • codeine was first isolated by french chemist Pierre jean Go BK in 18 32.

  • Then looking to develop a non addictive version of morphine.

  • In 18 74 english chemist Charles Wright instead created heroin, also known as diamorphine number one penicillin.

  • This is probably the most famous case of accidentally stumbling onto a medical marvel.

  • In 1928, Scottish physician Alexander Fleming returned to his laboratory after a vacation.

  • He then examined his culture plates of staphylococcus.

  • He had left out and realized one was open inside a mold had gotten in and had amazingly stopped the spread of the bacteria.

  • This mold was penicillium Rubens, while Mold has been used to treat infections for centuries.

  • This remarkable observation led to one of the world's first antibiotic medications with penicillin in 1942.

  • Since then, an estimated 200 million lives at least have been saved.

  • Thanks to this accidental discovery.

  • If certain British doctors never asked what is this fungus, we wouldn't today have penicillin, correct.

Okay, I think it's time to turn down the morphine trip.

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