Cancer? Heart attacks? Diabetes?

The answer is actually none of these;

it's Alzheimer's disease.

Every 67 seconds,

someone in the United States is diagnosed with Alzheimer's.

As the number of Alzheimer's patients triples by the year 2050,

caring for them, as well as the rest of the aging population,

will become an overwhelming societal challenge.

My family has experienced firsthand

the struggles of caring for an Alzheimer's patient.

Growing up in a family with three generations,

I've always been very close to my grandfather.

When I was four years old,

my grandfather and I were walking in a park in Japan

when he suddenly got lost.

It was one of the scariest moments I've ever experienced in my life,

and it was also the first instance that informed us

that my grandfather had Alzheimer's disease.

Over the past 12 years, his condition got worse and worse,

and his wandering in particular caused my family a lot of stress.

My aunt, his primary caregiver,

really struggled to stay awake at night to keep an eye on him,

and even then often failed to catch him leaving the bed.

I became really concerned about my aunt's well-being

as well as my grandfather's safety.

I searched extensively for a solution that could help my family's problems,

but couldn't find one.

Then, one night about two years ago,

I was looking after my grandfather and I saw him stepping out of the bed.

The moment his foot landed on the floor,

I thought, why don't I put a pressure sensor on the heel of his foot?

Once he stepped onto the floor and out of the bed,

the pressure sensor would detect an increase in pressure caused by body weight

and then wirelessly send an audible alert to the caregiver's smartphone.

That way, my aunt could sleep much better at night

without having to worry about my grandfather's wandering.

So now I'd like to perform a demonstration of this sock.

Could I please have my sock model on the stage?

Great.

So once the patient steps onto the floor --

(Ringing) --

an alert is sent to the caregiver's smartphone.

Thank you. (Applause)

Thank you, sock model.

So this is a drawing of my preliminary design.

My desire to create a sensor-based technology

perhaps stemmed from my lifelong love for sensors and technology.

When I was six years old,

an elderly family friend fell down in the bathroom

and suffered severe injuries.

I became concerned about my own grandparents

and decided to invent a smart bathroom system.

Motion sensors would be installed inside the tiles of bathroom floors

to detect the falls of elderly patients whenever they fell down in the bathroom.

Since I was only six years old at the time

and I hadn't graduated from kindergarten yet,

I didn't have the necessary resources and tools to translate my idea into reality,

but nonetheless, my research experience

really implanted in me a firm desire to use sensors to help the elderly people.

I really believe that sensors can improve the quality of life of the elderly.

When I laid out my plan, I realized that I faced three main challenges:

first, creating a sensor;

second, designing a circuit;

and third, coding a smartphone app.

This made me realize that my project was actually much harder to realize

than I initially had thought it to be.

First, I had to create a wearable sensor that was thin and flexible enough

to be worn comfortably on the bottom of the patient's foot.

After extensive research and testing of different materials like rubber,

which I realized was too thick to be worn snugly on the bottom of the foot,

I decided to print a film sensor

with electrically conductive pressure-sensitive ink particles.

Once pressure is applied, the connectivity between the particles increases.

Therefore, I could design a circuit that would measure pressure

by measuring electrical resistance.

Next, I had to design a wearable wireless circuit,

but wireless signal transmission consumes lots of power

and requires heavy, bulky batteries.

Thankfully, I was able to find out about the Bluetooth low energy technology,

which consumes very little power and can be driven by a coin-sized battery.

This prevented the system from dying in the middle of the night.

Lastly, I had to code a smartphone app that would essentially transform

the care-giver's smartphone into a remote monitor.

For this, I had to expand upon my knowledge of coding with Java and XCode

and I also had to learn about how to code for Bluetooth low energy devices

by watching YouTube tutorials and reading various textbooks.

Integrating these components, I was able to successfully create two prototypes,

one in which the sensor is embedded inside a sock,

and another that's a re-attachable sensor assembly

that can be adhered anywhere that makes contact

with the bottom of the patient's foot.

I've tested the device on my grandfather for about a year now,

and it's had a 100 percent success rate

in detecting the over 900 known cases of his wandering.

Last summer, I was able to beta test my device

at several residential care facilities in California,

and I'm currently incorporating the feedback

to further improve the device into a marketable product.

Testing the device on a number of patients

made me realize that I needed to invent solutions

for people who didn't want to wear socks to sleep at night.

So sensor data, collected on a vast number of patients,

can be useful for improving patient care

and also leading to a cure for the disease, possibly.

For example, I'm currently examining

correlations between the frequency of a patient's nightly wandering

and his or her daily activities and diet.

One thing I'll never forget is when my device first caught

my grandfather's wandering out of bed at night.

At that moment, I was really struck by the power of technology

to change lives for the better.

People living happily and healthfully --

that's the world that I imagine.

Thank you very much.

(Applause)