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Millions of Americans use caffeinated beverages every day as a pick-me-up.
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It is after all the world's most popular drug.
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And with new caffeine infused products like energy drinks, gum and even beef jerky hitting the shelves,
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our love affair with caffeine shows absolutely no signs of slowing down.
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Caffeine is an interesting drug because when it enters the body it breaks up into three different yet very similar molecules.
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When metabolized in the liver, enzymes chisel off one of three methyl groups
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to form these three metabolites with three different effects on your body:
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Theobromine, paraxanthine, and theophylline.
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While in the brain, this caffeine party crashes adenosine receptors blocking the normal guest, adenosine from doing its job.
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Adenosine is responsible for slowing down nerve activity in your brains giving us the cue to calm down and take a nap.
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Also adenosine is responsible for regulating neurotransmitters in the brain such as dopamine.
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As you can see, adenosine is also quite similar to caffeine in structure,
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which is why caffeine binds so easily to the adenosine protein receptors.
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Once connected, caffeine increases the activity in neurotransmitters like dopamine,
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ultimately leading to heightened brain activity.
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Then the three metabolites perform their own specific functions.
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Theobromine increases oxygen and nutrient flow to the brain.
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Paraxanthine enhances your body's athletic performance by increasing the rate a fat breakdown to fuel muscle activity.
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Theophylline increases your heart rate and reinforces your ability to concentrate.
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And although these effects come together to produce a state of wakefulness,
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too much caffeine can turn sour pretty quick.
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At higher doses caffeine is known to cause jitters, anxiety and just general all-around discomfort.
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For this reason scientists have found four hundred milligrams is the safest average dose of caffeine for adults.
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To put that into perspective, that'll be around three eight-ounce cups of coffee,
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five eight-ounce Red Bulls or a whopping eight cups black tea.
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And on a side note site it's also found that caffeine becomes toxic around 10 grams,
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which works out to be about seventy five cups of coffee, or 180 cups black tea.
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However, the lethal limit does vary widely from person to person.
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Hey thanks for watching folks.
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Stay tuned next week, we've got more science coming your way that can only make you smarter.
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Oh and if you have any chemistry themed questions, make sure you post them in the comments, they might be answered in upcoming videos.