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  • A Level of Biology_ Nervous System 4-Ecstacy and Serotonin

  • Hi, and welcome to my fourth video in this series. Today, were going to be looking

  • at the relationship between ecstasy and serotonin in the brain.

  • This diagram shows two neurones. This is your pre-synaptic neurone and this one is your

  • post-synaptic neurone; again, pre meaning before, and post meaning after.

  • These are neurones in the brain and these are the neurones that control things like your mood and happiness.

  • The drug that were looking at today is ecstasy otherwise known as sometimes MDMA.

  • What that causes is that causes a release a chemical called serotonin.

  • Serotonin is represented on the diagrams by these little yellow circles and theyre the neurotransmitter

  • between the nerve cells in the brain that control things like mood and happiness.

  • Now, what usually happens is that the serotonin is usually recycled and then put back into

  • the pre-synaptic neuron. So, this diagram here shows essentially how its reset. So,

  • now, when another impulse comes in, it’s then free to release more serotonin into the

  • synapse. But what happens when you take ecstasy is the serotonin is not taken back up into

  • the pre-synaptic neurone like it is here. Essentially, what happens is this, the serotonin,

  • is blocked from reentering here and so you have an increased level of serotonin in the

  • synapse. So, these neurones consistently fire, hence,

  • the feelings of happiness and pleasure that you get when the drug is taken. Then, not all research down in this area is

  • absolutely conclusive, but for most of the evidence that we have currently, there seems

  • to be a link between taking MDMA and ecstasy and some forms of depression. Like I said,

  • this isn’t a guarantee; taking ecstasy and MDMA doesn’t guarantee depression but it

  • increases your risk. A bit like if youre drinking too much, the increase risk of liver

  • disease is much higher than if you did not. In summary, the neuro transmitter and the

  • brain that controls mood and happiness is serotonin and essentially taking a drug like

  • ecstasy or MDMA increases the level of serotonin in the brain. It does this because it stops

  • it being reabsorbed back into the presynaptic neurone. This causes the neurones in the brain

  • that control happiness and mood to fire more regularly and this increases the feelings

  • of pleasure and elation. It has been shown, however, that prolonged use of ecstasy can

  • lead to depression.

A Level of Biology_ Nervous System 4-Ecstacy and Serotonin

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B2 UK TED serotonin ecstasy synaptic mdma happiness

【TED】Nervous System [4]: Ecstasy and Serotonin (A Level Biology)

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