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Transcriber: Theresa Ranft Reviewer: Peter van de Ven
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I want to lead here
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by talking a little bit about my credentials to bring this up with you,
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because, quite honestly, you really, really should not listen
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to any old person with an opinion about COVID-19.
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(Laughter)
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So, I've been working in global health for about 20 years,
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and my specific technical specialty is in health systems
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and what happens when health systems experience severe shocks.
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I've also worked in global-health journalism.
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I've written about global health and biosecurity
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for newspapers and web outlets,
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and I published a book a few years back
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about the major global health threats facing us as a planet.
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I have supported and led epidemiology efforts
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that range from evaluating Ebola treatment centers
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to looking at transmission of tuberculosis in health facilities
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and doing avian influenza preparedness.
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I have a master's degree in International Health.
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I'm not physician. I'm not a nurse.
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My specialty isn't patient care or taking care of individual people.
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My specialty is looking at populations and health systems -
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what happens when diseases move on the large level.
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If we're ranking sources of global-health expertise
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on a scale of 1 to 10 -
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1 is some random person ranting on Facebook,
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and 10 is the World Health Organization -
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I'd say you can probably put me at like a 7 or an 8.
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So, keep that in mind as I talk to you.
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I'll start with the basics here
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because I think that's gotten lost
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in some of the media noise around COVID-19.
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So, COVID-19 is a coronavirus,
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and coronaviruses are a specific subset of virus,
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and they have some unique characteristics as viruses.
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They use RNA instead of DNA as their genetic material,
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and they're covered in spikes on the surface of the virus,
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and they use those spikes to invade cells.
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Those spikes are the corona in coronavirus.
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COVID-19 is known as a novel coronavirus
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because, until December, we'd only heard of six coronaviruses.
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COVID-19 is the seventh.
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It's new to us,
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it just had its gene sequencing, it just got its name -
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that's why it's novel.
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If you remember SARS - severe acute respiratory syndrome -
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or MERS - Middle East respiratory syndrome,
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those were coronaviruses,
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and they're both called respiratory syndromes
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because that's what coronaviruses do.
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They go for your lungs.
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Don't make you puke,
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they don't make you bleed from the eyeballs,
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they don't make you hemorrhage, they head for your lungs.
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COVID-19 is no different.
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It causes a range of respiratory symptoms
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that go from stuff like a dry cough and a fever
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all the way out to fatal viral pneumonia.
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And that range of symptoms is one of the reasons
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it's actually been so hard to track this outbreak.
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Plenty of people get COVID-19,
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but so gently, their symptoms are so mild
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that they don't even go to a health care provider.
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They don't register in the system.
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Children, in particular, have it very easy with COVID-19,
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which is something we should all be grateful for.
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Coronaviruses are zoonotic,
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which means that they transmit from animals to people.
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Some coronaviruses, like COVID-19, also transmit person to person.
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The person-to-person ones travel faster and travel farther,
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just like COVID-19.
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Zoonotic illnesses are really hard to get rid of
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because they have an animal reservoir.
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One example is avian influenza,
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where we can abolish it in farmed animals,
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in turkeys, in ducks,
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but it keeps coming back every year because it's brought to us by wild birds.
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You don't hear a lot about it
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because avian influenza doesn't transmit person to person,
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but we have outbreaks in poultry farms every year all over the world.
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COVID-19 most likely skipped from animals into people
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at a wild animal market in Wuhan, China.
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Now for the less basic parts.
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This is not the last major outbreak we're ever going to see.
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There's going to be more outbreaks, and there's going to be more epidemics.
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That's not a maybe; that's a given.
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And it's a result of the way that we, as human beings,
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are interacting with our planet.
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Human choices are driving us into a position
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where we're going to see more outbreaks.
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Part of that is about climate change and the way a warming climate
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makes the world more hospitable to viruses and bacteria.
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But it's also about the way we're pushing into the last wild spaces on our planet.
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When we burn and plow the Amazon rain forest
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so that we can have cheap land for ranching,
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when the last of the African bush gets converted into farms,
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when wild animals in China are hunted to extinction,
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human beings come into contact with wildlife populations
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that they've never come into contact with before,
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and those populations have new kinds of diseases:
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bacteria, viruses - stuff we're not ready for.
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Bats, in particular, have a knack for hosting illnesses
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that can infect people.
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But they're not the only animals that do it.
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So as long as we keep making our remote places less remote,
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the outbreaks are going to keep coming.
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We can't stop the outbreaks with quarantine or travel restrictions.
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That's everybody's first impulse:
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Let's stop the people from moving, let's stop this outbreak from happening.
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But the fact is it's really hard to get a good quarantine in place.
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It's really hard to set up travel restrictions.
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Even the countries that have made serious investments in public health,
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like the US and South Korea,
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can't get that kind of restriction in place fast enough
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to actually stop an outbreak instantly.
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There's logistical reasons for that, and there's medical reasons.
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If you look at COVID-19,
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right now, it's seems like it could have a period
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where you're infected and show no symptoms
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that's as long as 24 days.
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So people are walking around with this virus
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showing no signs.
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They're not going to get quarantined.
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Nobody knows they need quarantining.
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There's also some real costs to quarantine and to travel restrictions.
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Humans are social animals,
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and they resist when you try to hold them into place
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and when you try to separate them.
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We saw in the Ebola outbreak
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that as soon as you put a quarantine in place,
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people start trying to evade it.
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Individual patients, if they know there's a strict quarantine protocol,
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may not go for health care
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because they're afraid of the medical system,
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or they can't afford care,
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and they don't want to be separated from their family and friends.
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Politicians, government officials,
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when they know they're going to get quarantined,
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if they talk about outbreaks and cases,
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may conceal real information
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for fear of triggering a quarantine protocol.
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And, of course, these kinds of evasions and dishonesty
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are exactly what makes it so difficult to track a disease outbreak.
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We can get better at quarantines and travel restrictions,
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and we should.
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But they're not our only option,
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and they're not our best option for dealing with these situations.
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The real way for the long haul to make outbreaks less serious
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is to build the global health system
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to support core health-care functions in every country in the world
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so that all countries, even poor ones,
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are able to rapidly identify and treat new infectious diseases as they emerge.
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China's taken a lot of criticism for its response to COVID-19.
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But the fact is, What if COVID-19 had emerged in Chad,
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which has 3.5 doctors for every 100,000 people?
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What if it had emerged in the Democratic Republic of Congo,
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which just released its last Ebola patient from treatment?
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The truth is countries like this don't have the resources
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to respond to an infectious disease,
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not to treat people
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and not to report on it fast enough to help the rest of the world.
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I led an evaluation of Ebola treatment centers in Sierra Leone.
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And the fact is
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that local doctors in Sierra Leone identified the Ebola crisis very quickly.
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First as a dangerous, contagious hemorrhagic virus,
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and then as Ebola itself.
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But having identified it, they didn't have the resources to respond.
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They didn't have enough doctors or hospital beds,
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and they didn't have enough information about how to treat Ebola
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or how to implement infection control.
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Eleven doctors died in Sierra Leone of Ebola.
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The country only had 120 when the crisis started.
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By way of contrast,
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Dallas Baylor Medical Center has more than 1,000 physicians on staff.
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These are the kinds of inequities that kill people.
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First, they kill the poor people when the outbreaks start,
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and then they kill people all over the world
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when the outbreaks spread.
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If we really want to slow down these outbreaks
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and minimize their impact,
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we need to make sure that every country in the world
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has the capacity to identify new diseases, treat them,
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and report about them so they can share information.
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COVID-19 is going to be a huge burden on health systems.
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I'm not going to talk about death rates in this talk
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because, frankly, nobody can agree on the COVID-19 death rates right now.
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But one number we can agree on
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is that about 20% of people infected with COVID-19
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are going to need hospitalization.
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Our US medical system can just barely cope with that.
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But what's going to happen in Mexico?
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COVID-19 has also revealed some real weaknesses
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in our global health supply chains.
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Just-in-time ordering LEAN systems are great when things are going well,
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but in a time of crisis, what it means is we don't have any reserves.
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If a hospital or a country runs out of face masks
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or personal protective equipment,
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there's no big warehouse full of boxes that we can go to get more.
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You have to order more from the supplier, wait for them to produce it,
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and you have to wait for them to ship it, generally, from China.
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That's a time lag at a time when it's most important to move quickly.
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If we'd been perfectly prepared for COVID-19,
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China would have identified the outbreak faster.
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They would have been ready to provide care to infected people
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without having to build new buildings.
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They would have shared honest information with citizens
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so that we didn't see these crazy rumors spreading on social media in China.
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And they would have shared information with global health authorities
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so that they could start reporting to national health systems
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and getting ready for when the virus spread.
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National health systems would then have been able
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to stockpile the protective equipment they needed
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and train health care providers on treatment and infection control.
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We'd have science-based protocols for what to do when things happen,
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like cruise ships have infected patients.
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And we'd have real information going out to people everywhere,
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so we wouldn't see embarrassing, shameful incidents as xenophobia,
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like Asian-looking people getting attacked on the street in Philadelphia.
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But even with all that in place, we would still have outbreaks.
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The choices we're making about how we occupy this planet
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make that inevitable.
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As far as we have an expert consensus on COVID-19, it's this:
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here in the US and globally,
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it's going to get worse before it gets better.
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We're seeing cases of human transmission
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that aren't from returning travel,
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that are just happening in the community.
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And we're seeing people infected with COVID-19
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when we don't even know where the infection came from.
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Those are signs of an outbreak that's getting worse,
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not an outbreak that's under control.
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It's depressing, but it's not surprising.
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Global health experts, when they talk about the scenario of new viruses,
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this is one of the scenarios that they look at.
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We all hoped we'd get off easy.
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But when experts talk about viral planning,
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this is the kind of situation and the way they expect the virus to move.
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I want to close here with some personal advice.
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Wash your hands!
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Wash your hands a lot!
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I know you already wash your hands a lot because you're not disgusting.
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But wash your hands even more.
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Set up cues and routines in your life to get you to wash your hands.
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Wash your hands every time you enter and leave a building.
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Wash your hands when you go in and come out of a meeting.
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Get rituals there based around handwashing.